Results 1 to 10 of about 376,554 (172)

Gas-liquid chromatography-mass spectrometry of synthetic ceramides

open access: hybridJournal of Lipid Research, 1969
Two series of ceramides with either sphingosine (sphing-4-enine) or sphinganine as base and with one of the saturated fatty acids C16, C18, C20, C22, C24, C26, or oleic acid were analyzed as the 1,3-di-O-trimethylsilyl ether derivatives by gas ...
Bengt Samuelsson, Karin Samuelsson
doaj   +2 more sources

Chemical Composition of Leaves, Stem, and Roots of Peperomia pellucida (L.) Kunth

open access: yesMolecules, 2022
Peperomia pellucida is a species known in the Amazon as “erva-de-jabuti” that has been used in several therapeutic applications based on folk medicine.
Paulo Wender P. Gomes   +10 more
doaj   +1 more source

Putative Identification of New Phragmaline-Type Limonoids from the Leaves of Swietenia macrophylla King: A Case Study Using Mass Spectrometry-Based Molecular Networking

open access: yesMolecules, 2023
Swietenia macrophylla King is a plant commonly known as Brazilian mahogany. The wood from its stem is highly prized for its exceptional quality, while its leaves are valued for their high content of phragmalin-type limonoids, a subclass of compounds ...
José Diogo E. Reis   +7 more
doaj   +1 more source

Antiviral Plants from Marajó Island, Brazilian Amazon: A Narrative Review

open access: yesMolecules, 2022
Diseases caused by viruses are a global threat, resulting in serious medical and social problems for humanity. They are the main contributors to many minor and major outbreaks, epidemics, and pandemics worldwide.
Paulo Wender P. Gomes   +9 more
doaj   +1 more source

Sampling the proteome by emerging single-molecule and mass-spectrometry methods [PDF]

open access: yesNat Methods 20, 339--346 (2023), 2022
Mammalian cells have about 30,000-fold more protein molecules than mRNA molecules. This larger number of molecules and the associated larger dynamic range have major implications in the development of proteomics technologies. We examine these implications for both liquid chromatography-tandem mass spectrometry (LC-MS/MS) and single-molecule counting ...
arxiv   +1 more source

Pitfall in the high-throughput quantification of whole blood cyclosporin A using liquid chromatography-tandem mass spectrometry [PDF]

open access: yes, 2005
In a growing number of laboratories the technique of liquid chromatography-tandem mass spectrometry is used for the quantification of cyclosporin A in whole blood, employing cyclosporin D as the internal standard. Cyclosporin A is extensively metabolized
Spöhrer, Ute, Vogeser, Michael
core   +2 more sources

Analysis of doping control samples using supercritical fluid chromatography-tandem mass spectrometry: Ready for routine use [PDF]

open access: yes, 2023
Supercritical fluid chromatography is proving to be a good separation and sample preparation tool for various analytical applications and, as such, has gained the attention of the anti-doping community.
Botrè, Francesco   +5 more
core   +1 more source

Anti-High Mobility Group Box-1 Monoclonal Antibody Attenuates Seizure-Induced Cognitive Decline by Suppressing Neuroinflammation in an Adult Zebrafish Model

open access: yesFrontiers in Pharmacology, 2021
Epilepsy is a chronic brain disease afflicting around 70 million global population and is characterized by persisting predisposition to generate epileptic seizures.
Yam Nath Paudel   +3 more
doaj   +1 more source

Mechanistic Insights into Alzheimer’s Disease Unveiled through the Investigation of Disturbances in Central Metabolites and Metabolic Pathways [PDF]

open access: yes, 2021
Hydrophilic metabolites are closely involved in multiple primary metabolic pathways and, consequently, play an essential role in the onset and progression of multifactorial human disorders, such as Alzheimer's disease.
Fernández-Recamales, Ángeles   +5 more
core   +4 more sources

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