Detection of Thiazide-Based Diuretics in Equine Urine by Liquid Chromatography/Mass Spectrometry [PDF]
Spiros D. Garbis, Luke Hanley, S. Kalita
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This study develops itaconate‐based polymer microparticles (IA‐MPs) for macrophage‐targeted intracellular delivery, overcoming the limitations of traditional itaconate administration. IA‐MPs achieve controlled release through phagocytosis, reducing pro‐inflammatory cytokine expression and reprogramming macrophage metabolism toward glycolysis.
Kaitlyn E. Woodworth+10 more
wiley +1 more source
Muramic acid detection in mammalian tissues by gas-liquid chromatography-mass spectrometry
Alvin Fox+2 more
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Dendrimer Conjugates with PD‐L1‐Binding Peptides Enhance In Vivo Antitumor Immune Response
In this paper, a novel nanoparticle scaffold composed of dendrimers conjugated with peptide‐based immune checkpoint inhibitors, enhancing drug delivery efficacy is introduced. By conjugating PD‐L1‐binding peptides to dendrimers, multivalent binding effects are harnessed, resulting in enhanced binding affinity, prolonged half‐life, and improved ...
DaWon Kim+11 more
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TraianProt: a user-friendly R shiny application for wide format proteomics data downstream analysis [PDF]
Summary: Mass spectrometry coupled to liquid chromatography (LC-MS/MS) is a powerful technique for the charac-terisation of proteomes. However, the diverse software platforms available for processing the raw proteomics data, each produce their own output format, making the extraction of meaningful and interpretable results a difficult task.
arxiv
Enantiomeric separation and detection by high-performance liquid chromatography-mass spectrometry of 2-arylpropionic acids derivatized with benzofurazan fluorescent reagents [PDF]
Tomofumi Santa+3 more
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Synthetic Aspects and Characterization Needs in MOF Chemistry – from Discovery to Applications
Overcoming the challenges of phase discovery, synthesis optimization and scale‐up, characterization, and computational studies is essential to accelerate the large‐scale application of MOFs. Life‐cycle analyses and techno‐economic analyses need to be performed to realistically assess their potential for industrial relevance.
Bastian Achenbach+4 more
wiley +1 more source
Arsenic Speciation of Aqueous Environmental Samples by Derivatization with Thioglycolic Acid Methylester and Capillary Gas--Liquid Chromatography--Mass Spectrometry [PDF]
Fred Claussen
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Stem cell spheroids, produced via a high‐throughput microfabrication technique, are transported within a vortex generated at the outlet channels of a cross‐slot millifluidic chip. For Reynolds number exceeding 170–200, intermittent high shear stresses applied to each spheroid within the vortex trigger a massive release of biologically active ...
Elliot Thouvenot+8 more
wiley +1 more source