Results 61 to 70 of about 1,328,993 (311)
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Journal of Open Research Software, 2016 This paper aimed to develop a standalone application for optimizing flow rates in liquid chromatography (LC), gas chromatography (GC) and supercritical fluid chromatography (SFC). To do so, Van Deemter’s equation, Knox’ equation and Golay’s equation were
Joris Meurs
doaj +1 more source
Identification of a Widespread Palmitoylethanolamide Contamination in Standard Laboratory Glassware. [PDF]
, 2017 Introduction: Fatty acid ethanolamides (FAEs) are a family of lipid mediators that participate in a host of biological functions. Procedures for the quantitative analysis of FAEs include organic solvent extraction from biological matrices (e.g., blood ...
Angelini, Roberto +3 more
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Electrochemical Process for Diazinon Removal from Aqueous Media: Design of Experiments, Optimization, and DLLME-GC-FID Method for Diazinon Determination [PDF]
, 2015 In the present study, electrochemical process was studied via removal of diazinon (O,O-diethyl O-2-isopropyl-6-methylpyrimidin-4-yl phosphorothioate) as an insecticide/ acaricide organic case study.
Daraei, H. +4 more
core +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Review of centrifugal liquid-liquid chromatography using aqueous two-phase solvent (ATPS) systems: Its scale-up and prospects for the future production of high-value biologics [PDF]
, 2007 The future challenges in bioprocessing include developing new downstream processes for the purification and manufacture of the protein based medicines of the future to relieve the predicted bottleneck being produced by increasingly high titres from ...
Sutherland, I A
core
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
MoleculesThis review is dedicated to sustainable practices in liquid chromatography. HPLC and UHPLC methods contribute significantly to routine analytical techniques.
Sami El Deeb
doaj +1 more source
Determination of β-Galactooligosaccharides by Liquid Chromatography
International Journal of Analytical Chemistry, 2014 Beta-galactooligosaccharides (GOS) are oligosaccharides normally produced industrially by transgalactosylation of lactose. They are also present naturally in the milk of many animals including humans and cows. GOS are thought to be good for health, being
Sean Austin +4 more
doaj +1 more source
Analysis of α-lipoprotein cholesterol in 50 μl of plasma
Journal of Lipid Research, 1974 A micromethod for quantitation of α-lipoprotein cholesterol was devised for gas–liquid chromatography to minimize plasma sample size and facilitate lipid studies using capillary blood from children or small animals. α-Lipoprotein cholesterol was measured
R.F. Lutmer +7 more
doaj +1 more source