Results 51 to 60 of about 279,117 (297)

VAN LCOS microdisplays: a decade of technological evolution [PDF]

open access: yes, 2011
—Microdisplays of the liquid crystals on silicon (LCOS) type have gone through a rapid evolution during the last decade. We present an overview of how vertically aligned nematic (VAN) LCOS have evolved from an attractive, but notoriously difficult and ...
Cuypers, Dieter   +2 more
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Full degree-of-freedom polarization hologram by freeform exposure and inkjet printing

open access: yesPhotoniX, 2023
Since the invention of holography by Dennis Gabor, the fabrication of holograms has mainly relied on direct recording of wavefront by engraving the intensity fringes of interfering electric fields into the holographic material. The degree-of-freedom (DoF)
Jianghao Xiong   +4 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Tunable liquid crystal grating based holographic 3D display system with wide viewing angle and large size

open access: yesLight: Science & Applications, 2022
A tunable liquid crystal grating-based holographic 3D display system is proposed with wide viewing angle and large size.
Yi-Long Li   +6 more
doaj   +1 more source

野球用スコアボードの試作 [PDF]

open access: yes, 2019
I made the Baseball Scoreboard Application software for iPhone/iPad. To connect a liquid crystal display, the picture on the iPhone/iPad is output on the display, some audiences can watch it.
布施川, 秀紀
core  

Compensation for time fluctuations of phase modulation in a liquid-crystal-on-silicon display by process synchronization in laser materials processing [PDF]

open access: yes, 2011
We demonstrate the adverse influence of temporal fluctuations of the phase modulation of a spatial light modulator (SLM) display device on nanosecond laser micromachining.
Beck, Rainer J   +3 more
core   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

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