Results 71 to 80 of about 175,341 (310)

Stiffening Liquid Crystal Elastomers with Liquid Crystal Inclusions

Advanced Materials
Abstract Liquid crystal elastomers (LCEs) are promising building blocks for soft robots, given their large, programmable, reversible, and stimuli‐responsive shape change. Enhancing LCEs’ stiffness and toughness has been a longstanding desire previously explored by reinforcing them with fillers, crystalline microdomains, and ...
Sahad Vasanji, Matthew Gene Scarfo, Arwa Alyami, Tizazu H. Mekonnen, Parsin Hajireza, Mohand O. Saed, Antal Jákli, Hamed Shahsavan   +7 more
openaire   +4 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Photothermal Transport for Guiding Nanoparticles Through the Vitreous Humor

Advanced Science
Visual impairments affect over 2.2 billion people worldwide, yet delivering drugs to the posterior segment of the eye, including the retina, remains a major challenge. Intravitreal injection, the standard administration route, often results in suboptimal
Léa Guerassimoff, Yera Ussembayev, Louise De Clerck, Deep Punj, Martijn van den Broek, Filip Beunis, Katrien Remaut, Kevin Braeckmans, Stefaan C. De Smedt, Félix Sauvage   +9 more
doaj   +1 more source

Design and verification of an umbrella shaped narrow band - UWB antenna pair for MIMO applications using characteristic mode analysis

e-Prime: Advances in Electrical Engineering, Electronics and Energy
Using characteristic mode analysis (CMA), a pair of ultra-wideband (UWB) and narrow band antennas is made. The Multiple Input Multiple Output (MIMO) configuration incorporates a circular monopole to attain UWB functionality, while an umbrella-shaped ...
Chandra Suresh Ankireddy, T. Sreenivasulu Reddy, B T P Madhav   +2 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Enhancement of the Coupling Gain in GaAs-Liquid Crystal Hybrid Devices [PDF]

, 2012
In this work the evanescent space-charge field generated in semi-insulating GaAs semiconductor substrates was used to reorient the liquid crystals molecules sandwiched between them to study the energy exchange in two-wave mixing experiments. We show that
Carla Berrospe Rodríguez, RUBEN RAMOS GARCIA   +1 more
core  

Electrically tunable, optically induced dynamic and permanent gratings in dye-doped liquid crystals [PDF]

, 2002
We report on further experimental studies of the ac field response of transient and permanent gratings written with visible light in both planar and homeotropic, dye-doped liquid crystal cells.
Cudney, Roger S., Kaczmarek, Malgosia, Shih, Min-Yi, Khoo, Iam-Choon   +3 more
core   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Tuning the Electrical Resistivity of Molecular Liquid Crystals for Electro-Optical Devices

Engineering Proceedings
Modern applications of molecular liquid crystals span from high-resolution displays for augmented and virtual reality to miniature tunable lasers, reconfigurable microwave devices for space exploration and communication, and tunable electro-optical ...
Michael Gammon, Iyanna Trevino, Michael Burnes, Noah Lee, Abdul Saeed, Yuriy Garbovskiy   +5 more
doaj   +1 more source