Results 71 to 80 of about 712,786 (306)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Engineering considerations on the use of liquid/liquid two-phase systems as a cell culture platform [PDF]

, 2016
BACKGROUND: Application of perfluorocarbon based liquid/liquid two-phase systems for cell culture expansion has been investigated at small scale for more than 30 years and it has been established that such systems are able to support the survival of a ...
Andrzej W. Pacek (7128608), Nienow, Alvin W., Mariana P. Hanga (4810689), Coopman, Karen, Hanga, Mariana P., Halina Murasiewicz (6592934), Murasiewicz, Halina, Hewitt, Christopher J., Karen Coopman (1171644), Alvin W. Nienow (7127162), Pacek, Andrzej W., Christopher J. Hewitt (7127150)   +11 more
core   +2 more sources

Swimming in liquid culture

, 2019
Swimming measurements for the cells growing in liquid ...
Honda (7258712)
core   +1 more source

Liquid marble – a high-yield micro-photobioreactor platform

, 2023
Liquid marbles are liquid droplets coated with micro/nano particles. Liquid marbles have been used as a micro reactor platform for various applications.
Nguyen, Nam-Trung, Pradip Singha, Nhat-Khuong Nguyen, Chin Hong Ooi, Nam-Trung Nguyen, Tran, Du Tuan, Burford, Michele, Gregor Kijanka, Du Tuan Tran, Nguyen, Nhat-Khuong, Ann Chuang, Michele Burford, Chuang, Ann, Singha, Pradip, Kijanka, Gregor, Ooi, Chin Hong   +15 more
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Saffron In Vitro Propagation: An Innovative Method by Temporary Immersion System (TIS), Integrated with Machine Learning Analysis

Horticulturae
The propagation of Crocus sativus L. relies exclusively on corm multiplication. As underground storage organs, corms are susceptible to a wide range of pathogens, environmental stresses, and diseases, making traditional propagation methods often ...
Waed Tarraf, Tolga İzgü, Özhan Şimşek, Nunzia Cicco, Carla Benelli   +4 more
doaj   +1 more source

Increased productivity of Clostridium acetobutylicum fermentation of acetone, butanol, and ethanol by pervaporation through supported ionic liquid membrane

, 2008
Pervaporation proved to be one of the best methods to remove solvents out of a solvent producing Clostridium acetobutylicum culture. By using an ionic liquid (IL)-polydimethylsiloxane (PDMS) ultrafiltration membrane (pore size 60 nm), we could guarantee ...
Izak, P., Schwarz, K.M., Wolfgang Ruth, Kragl, U., Bahl, H., Hubert Bahl, Ruth, W., Katrin Schwarz, Udo Kragl, Pavel Izák   +9 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Misconceptions of culture in cross cultural business and management studies

, 2009
In this paper, I critique the cliched representations of culture in the general context of cross-cultural business and management studies. My primary objective is to demonstrate how a lack of conceptualisation of culture has resulted in the proliferation
Jafari, Aliakbar
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source