Results 31 to 40 of about 368,842 (254)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Numerical Study of Liquid Hydrogen Internal Flow in Liquid Hydrogen Storage Tank

Energies
As a key zero-carbon energy carrier, the accurate measurement of liquid hydrogen flow in its industrial chain is crucial. However, the ultra-low temperature, ultra-low density and other properties of liquid hydrogen can introduce calibration errors.
Xiang Li, Qun Wei, Lianyan Yu, Xiaobin Zhang, Yiting Zou, Yongcheng Zhu, Yanbo Peng, Daolin Wang, Zexian Zhu, Xianlei Chen, Yalei Zhao, Chengxu Tu, Fubing Bao   +12 more
doaj   +1 more source

ON THE MICROSCOPIC STRUCTURE OF LIQUID HYDROGENS [PDF]

Condensed Matter Physics, 2001
Among the quantum liquids, the hydrogens cover an interesting position between liquid helium, where quantum exchange gives rise to the macroscopic phenomenon of superfluidity, and neon, where quantum effects are relatively small, so that its features can be evaluated by perturbation methods with reference to a classical system.
Zoppi M., Celli M., Bafile U., Guarini E., Neumann M.   +4 more
openaire   +3 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A Comprehensive Review on Material Compatibility and Safety Standards for Liquid Hydrogen Cargo and Fuel Containment Systems in Marine Applications

Journal of Marine Science and Engineering, 2023
As the maritime industry’s emphasis on sustainable fuels has increased, liquid hydrogen (LH2) has emerged as a promising alternative due to its high energy density and zero-emission characteristics.
Myung-Sung Kim, Kang Woo Chun
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Modelling of Liquid Hydrogen Boil-Off

Energies, 2022
A model has been developed and implemented in the software package BoilFAST that allows for reliable calculations of the self-pressurization and boil-off losses for liquid hydrogen in different tank geometries and thermal insulation systems.
Saif Z. S. Al Ghafri, Adam Swanger, Vincent Jusko, Arman Siahvashi, Fernando Perez, Michael L. Johns, Eric F. May   +6 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Assessment of Boil-Off Losses and Their Cost Implication during Liquid Hydrogen Tank Filling with and without Precooling

Energies
During liquid hydrogen bunkering into a cryogenic tank, boil-off losses occur due to the high thermal gradient between liquid hydrogen and the warm surface of the tank. This leads to gaseous hydrogen release. Such losses constitute a significant drawback
Bright Ebikemefa Okpeke, Cherif Ait Aider, Lars Baetcke, Sören Ehlers   +3 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source