Results 91 to 100 of about 2,993,633 (238)

Evaporative Heat and Mass Transfer from the Free Surface of a Liquid Wicked into a Bed of Spheres [PDF]

open access: yes, 2011
Evaporation of ethanol from square packed arrays of 3.95 mm diameter copper spheres in a transparent, enclosed chamber is investigated. The enclosure ensures that relatively saturated vapor conditions exist near the free surface. The desired heat flux is
Garimella, Suresh V.   +4 more
core   +1 more source

Interview with Jimmy Limit: "Recent Advancements"

open access: yes, 2014
Jimmy Limit\u27s "Recent Advancements" (18 Jan-4 May 2014) at Rodman Hall, St. Catharines, Ontario.
Limit, Jimmy
core   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Land subsidence potential in the Tahlab plain and the relationship between domestic wastewater and collapse in sewage wells in the Rig-Malek city, southeast of Zahedan [PDF]

open access: yesعلوم زمین خوارزمی
The Tehlab plain is located in the Hamoun Mashkil catchment in the south of Mirjavah region and along the Iran-Pakistan border. In most of the rural areas of this plain, especially in the northern parts of the plain along the border of Iran and Pakistan,
Reza Jahanshahi   +3 more
doaj  

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Soil Liquid Limit Determination Using a Single-Trial Methodology

open access: yesJournal of Engineering
A new model equation has been constructed to estimate the liquid limit value, using the rapid one point method. Data processing was carried out in Microsoft Excel and SPSS, visualizing and using 6,210 theoretical trial points, which resulted from 135 ...
Mohammed Yaseen Abdullah
doaj   +1 more source

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