Results 51 to 60 of about 548,988 (300)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Information Entropy of Liquid Metals [PDF]

open access: yesThe Journal of Physical Chemistry B, 2018
Correlations reduce the configurational entropies of liquids below their ideal gas limits. By means of first principles molecular dynamics simulations, we obtain accurate pair correlation functions of liquid metals, then subtract the mutual information content of these correlations from the ideal gas entropies to predict the absolute entropies over a ...
M. C. Gao, M. Widom
openaire   +3 more sources

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

A New Anisotropic Four-Parameter Turbulence Model for Low Prandtl Number Fluids

open access: yesFluids, 2021
Due to their interesting thermal properties, liquid metals are widely studied for heat transfer applications where large heat fluxes occur. In the framework of the Reynolds-Averaged Navier–Stokes (RANS) approach, the Simple Gradient Diffusion Hypothesis (
Giacomo Barbi   +2 more
doaj   +1 more source

Scaling Behavior of Heavy Fermion Metals

open access: yes, 2010
Strongly correlated Fermi systems are fundamental systems in physics that are best studied experimentally, which until very recently have lacked theoretical explanations.
Amusia, M. Ya.   +3 more
core   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Flexible Electronic Devices and Wearable Sensors Based on Liquid Metals

open access: yesMetalMat
Stretchable electronic devices play a key role in bridging various components, especially in flexible and complex multifunctional logic circuits, as well as in information recognition and transmission systems.
Xiang Li   +4 more
doaj   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

Ion density fluctuations in liquid metals: the strongly interacting ion-electron plasma

open access: yesCondensed Matter Physics, 2008
An unified description of liquid metals dynamics based on an interacting two-component model for the ion-electron plasma is tempted. The propagation velocity of the collective modes in alkali and polyvalent metals, derived from inelastic neutron and x ...
L.E.Bove, C.Petrillo, F.Sacchetti
doaj   +1 more source

Attributes, Fabrication, and Applications of Gallium‐Based Liquid Metal Particles

open access: yesAdvanced Science, 2020
This work discusses the attributes, fabrication methods, and applications of gallium‐based liquid metal particles. Gallium‐based liquid metals combine metallic and fluidic properties at room temperature.
Yiliang Lin   +2 more
doaj   +1 more source

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