Results 121 to 130 of about 4,935,227 (284)

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

A New Bubbling Extraction Tower: Toward Liquid-Liquid Solvent Extraction at Large Aqueous-to-Oil Phase Ratios

, 2015
Enrichment and recovery of valuable components in industrial waste waters by traditional liquid-liquid solvent extraction is not economic due to extremely low concentrations of those targets. Large-phase-ratio extraction exhibits potential advantages for
Liu, Jie, Wu, Huaizhi, Liu, Huizhou, Huang, Kun   +3 more
core   +1 more source

Influence of hydrogen content in tokamak scrape-off-layer on performance of lithium divertor

Nuclear Fusion
Self-replenishing liquid metal coatings are considered as a perspective divertor design able to withstand challenging particle and power loads of a fusion tokamak-reactor.
E.D. Marenkov, A.A. Pshenov
doaj   +1 more source

Evidence of radial Weibel instability in relativistic intensity laser-plasma interactions inside a sub-micron thick liquid target. [PDF]

Sci Rep, 2020
Ngirmang GK, Morrison JT, George KM, Smith JR, Frische KD, Orban C, Chowdhury EA, Roquemore WM.   +7 more
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Liquid Metal Target Prototypes for EURISOL Project: Goals And Future Challenges

Poster is dedicated to the concepts of the EURISOL multi megawatt liquid metal target. One of the possible versions could be windowless target concept.
Kravalis, Kalvis, Lielausis, Oļģerts, Platacis, Ernests, Ziks, Anatolijs   +3 more
core  

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Publisher Correction: Evidence of radial Weibel instability in relativistic intensity laser-plasma interactions inside a sub-micron thick liquid target. [PDF]

Sci Rep, 2020
Ngirmang GK, Morrison JT, George KM, Smith JR, Frische KD, Orban C, Chowdhury EA, Roquemore WM.   +7 more
europepmc   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source