Results 1 to 10 of about 17,313 (328)

Comparison of the dosimetry of scandium-43 and scandium-44 patient organ doses in relation to commonly used gallium-68 for imaging neuroendocrine tumours [PDF]

EJNMMI Physics
Background Several research groups have explored the potential of scandium radionuclides for theragnostic applications due to their longer half-lives and equal or similar coordination chemistry between their diagnostic and therapeutic counterparts, as ...
Carlos Vinícius Gomes, Bruno Melo Mendes, Lucas Paixão, Silvano Gnesin, Cristina Müller, Nicholas P. van der Meulen, Klaus Strobel, Telma Cristina Ferreira Fonseca, Thiago Viana Miranda Lima   +8 more
doaj   +4 more sources

In Vivo Trafficking of the Anticancer Drug Tris(8-Quinolinolato) Gallium (III) (KP46) by Gallium-68/67 PET/SPECT Imaging [PDF]

Molecules, 2023
KP46 (tris(hydroxyquinolinato)gallium(III)) is an experimental, orally administered anticancer drug. Its absorption, delivery to tumours, and mode of action are poorly understood. We aimed to gain insight into these issues using gallium-67 and gallium-68
Afnan M. F. Darwesh, Cinzia Imberti, Joanna J. Bartnicka, Fahad Al-Salemee, Julia E. Blower, Alex Rigby, Jayanta Bordoloi, Alex Griffiths, Michelle T. Ma, Philip J. Blower   +9 more
doaj   +2 more sources

Evaluation of Cyclotron Solid Target Produced Gallium-68 Chloride for the Labeling of [⁶⁸Ga]Ga-PSMA-11 and [⁶⁸Ga]Ga-DOTATOC [PDF]

Molecules
Gallium-68 is a widely used positron-emitting radionuclide in nuclear medicine, traditionally obtained from 68Ge/68Ga generators. However, increasing clinical demand has driven interest in alternative production methods, such as medical cyclotrons ...
Michał Jagodziński, Jakub Boratyński, Paulina Hamankiewicz, Łukasz Cheda, Witold Uhrynowski, Agnieszka Girstun, Joanna Trzcińska-Danielewicz, Zbigniew Rogulski, Marek Pilch-Kowalczyk   +8 more
doaj   +2 more sources

Failure of Gallium-68 citrate to detect large, enhancing, intracerebral central nervous system tuberculomas: A cautionary tale [PDF]

IDCases
Background: Gallium-68 citrate is an emerging diagnostic tool for the evaluation of infections. Its performance in brain infections is unknown. The available diagnostics for central nervous system tuberculosis are imprecise.
Selwyn Selva Kumar, Adrian Keith Noronha, Julie Hephzibah, Harshad Arvind Vanjare, Abi Manesh   +4 more
doaj   +2 more sources

Meningioma uptake of Gallium-PSMA-11 as a pitfall on positron emission tomography/computer tomography [PDF]

Acta Radiologica Open, 2021
Prostate cancer is the most common malignancy in men with high incidence of recurrence following treatment. Biochemical recurrence, as indicated by rising PSA levels following successful treatment of the primary disease, is a frequent encounter in ...
Michael Courtney, Ciaran Johnston, Afshin Nasoodi   +2 more
doaj   +2 more sources

Squamous cell carcinoma diagnosed as a suspected neuroendocrine tumor by gallium-68 DOTA-Tyr-octreotate positron emission tomography scan: A case report [PDF]

SAGE Open Medical Case Reports
Gallium-68 DOTA-Tyr 3 -octreotate positron emission tomography scan is an important radiologic tool for detecting neuroendocrine tumors. It detects neoplasms by capturing the tumor’s increased density of somatostatin receptor expression.
Tori Johnson, Shirley Chan-Sanchez, Tuan Pham, Mariangela Gomez   +3 more
doaj   +2 more sources

Development of the Purification Process of Gallium-68 Eluted from Germanium-68/Gallium-68 Generator

Siriraj Medical Journal
Objective: 68Ga has a half-life of 68 minutes, with 89% of its decay is through positron emission. It is available from generator systems and possesses suitable property for labeling radioligands.
Tossaporn Sriprapa, Thanete Doungta, Napamon Sritongkul, Malulee Tantawiroon   +3 more
doaj   +2 more sources

A heterodimeric radioligand labeled with gallium-68 targeting fibroblast activation protein [PDF]

EJNMMI Research
Background Fibroblast activation protein (FAP) targeting radiotracers have emerged as promising agents for cancer imaging and therapy. Recent advancements have focused on optimizing these agents for better tumor targeting and enhanced theranostic ...
Chengde Xie, Lei Peng, Hui Nie, Tianhong Yang, Renbo Wu, Dake Zhang, Fuhua Wen, Junyu Chen, Lingyu Xue, Xiangsong Zhang, Zhihao Zha, Jianjun Wang   +11 more
doaj   +2 more sources

Gallium-68 fibroblast activation protein inhibitor positron emission tomography in cardiovascular disease [PDF]

Frontiers in Nuclear Medicine, 2023
Gallium-68 fibroblast activation protein inhibitor [(68Ga)Ga-FAPI] is a new radiopharmaceutical positioning itself as the preferred agent in patients with malignant tumours, competing with 2-Deoxy-2-[18F]fluoro-d-glucose [2-(18F)FDG] using positron ...
Dineo Mpanya, Mike Sathekge, Mike Sathekge, Eric Klug, Eric Klug, Jenna Damelin, Stuart More, Bawinile Hadebe, Bawinile Hadebe, Mariza Vorster, Mariza Vorster, Nqoba Tsabedze   +11 more
doaj   +2 more sources

Side by side comparison of NOTA and DOTA for conjugation efficiency, gallium-68 labeling, and in vivo biodistribution of anti-mesothelin sdAb A1-His [PDF]

EJNMMI Radiopharmacy and Chemistry
Background Mesothelin is a glycoprotein overexpressed in various cancers, with limited expression in healthy tissues. The single-domain antibody (sdAb, or nanobody) A1-His has previously successfully been validated in mice for the SPECT imaging of ...
Émilien N’Guessan, Sandrine Bacot, Florian Raes, Julien Leenhardt, Thibault Guenard, Laurent Dumas, Catherine Ghezzi, Daniel Fagret, Charlotte Lombardi, Alexis Broisat, Mitra Ahmadi   +10 more
doaj   +2 more sources