Results 31 to 40 of about 44,757,379 (245)

Automated synthesis of [68Ga]Ga-FAPI-46 without pre-purification of the generator eluate on three common synthesis modules and two generator types

EJNMMI Radiopharmacy and Chemistry, 2022
Background The recent development of quinoline-based radiotracers, which act as fibroblast activation protein inhibitors (FAPIs), has shown promising preclinical and clinical advantages.
Ammar Alfteimi, Ulf Lützen, Alexander Helm, Michael Jüptner, Marlies Marx, Yi Zhao, Maaz Zuhayra   +6 more
doaj   +1 more source

Gallium-Strontium Phosphate Conversion Coatings for Promoting Infection Prevention and Biocompatibility of Magnesium for Orthopedic Applications

, 2022
Device-associated infections remain a clinical challenge. The common strategies to prevent bacterial infection are either toxic to healthy mammalian cells and tissue or involve high doses of antibiotics that can prompt long-term negative consequences. An
DE Tuipulotu (17114422), SM Man (17114419), N Birbilis (13356093), Y Qiu (6848966), MS Song (17114416), RW Li (15895460), PN Smith (16867380), DL Kaplan (9209630), XB Chen (14546609), I Cole (13306725)   +9 more
core   +2 more sources

Feasibility of Multiple Examinations Using 68Ga-Labelled Collagelin Analogues: Organ Distribution in Rat for Extrapolation to Human Organ and Whole-Body Radiation Dosimetry

Pharmaceuticals, 2016
Objectives: Fibrosis is involved in many chronic diseases. It affects the functionality of vital organs, such as liver, lung, heart and kidney. Two novel imaging agents for positron emission tomography (PET) imaging of fibrosis have previously pre ...
Irina Velikyan, Ulrika Rosenström, Thomas N. Bulenga, Olof Eriksson, Gunnar Antoni   +4 more
doaj   +1 more source

Case report 68Ga-DOTATATE of optic nerve sheath meningioma

American Journal of Ophthalmology Case Reports, 2021
We report a patient with an optic nerve sheath meningioma whose diagnosis and management were guided by using Gallium-68 DOTA-Tyr3-octreotatate (68Ga-DOTATATE).Positron Emission Tomography-Computed Tomography (PET-CT).
Adeleh Yarmohammadi, Peter J. Savino, Sonya J. Koo, Roland R. Lee   +3 more
doaj   +1 more source

Standardisation of conventional and advanced iterative reconstruction methods for Gallium-68 multi-centre PET-CT trials

EJNMMI Physics, 2021
Purpose To assess the applicability of the Fluorine-18 performance specifications defined by EANM Research Ltd (EARL), in Gallium-68 multi-centre PET-CT trials using conventional (ordered subset expectation maximisation, OSEM) and advanced iterative ...
Georgios Krokos, Lucy C. Pike, Gary J. R. Cook, Paul K. Marsden   +3 more
doaj   +1 more source

Cyclotron Production of Gallium-68 Radiopharmaceuticals Using the ⁶⁸Zn(p,n)⁶⁸Ga Reaction and Their Regulatory Aspects

Pharmaceutics, 2022
Designing and implementing various radionuclide production methods guarantees a sustainable supply, which is important for medical use. The use of medical cyclotrons for radiometal production can increase the availability of gallium-68 (68Ga ...
Zarif Ashhar, Muhammad Fakhrurazi Ahmad Fadzil, Muhamad Faiz Othman, Nor Azah Yusof, Muhammad Adib Abdul Onny, Noratikah Mat Ail, Siti Fatimah Abd Rahman   +6 more
doaj   +1 more source

COMPUTATION STUDY OF RADIOISOTOPES GALLIUM-68 (68Ga) PRODUCTION USING LONG-LIVED & HIGH ACTIVITY METHODS [PDF]

, 2022
Radioisotopes used for gamma-ray-based diagnostics have the main problem that imaging resolution quality.Gallium-68 is a positron (β+) emitting radioisotope that has better imaging resolution than gamma-based radioisotopes.
Martoprawiro, Muhamad Abdulkadir, Meliawati, Aristia Pratiwi, tursinah, Rasito, Arifah, Aminatus, Widayanti, Merika Indri, Setiadi, Yanuar, Rattyananda, Badra Sanditya, Badra Sanditya Rattyananda, Merika Indri Widayanti, Aminatus Arifah, Rasito Tursinah, Muhamad Abdulkadir Martoprawiro, Aristia Pratiwi Meliawati, Yanuar Setiadi   +13 more
core   +1 more source

Fused Zinc Target for the Production of Gallium Radioisotopes

Instruments, 2019
Gallium-68 is a popular radioisotope for positron emission tomography. To make gallium-68 more accessible, we developed a new solid target for medical cyclotrons.
Stefan Zeisler, Alan Limoges, Joel Kumlin, Jonathan Siikanen, Cornelia Hoehr   +4 more
doaj   +1 more source

Development of a Potential Gallium-68-Labelled Radiotracer Based on DOTA-Curcumin for Colon-Rectal Carcinoma: From Synthesis to In Vivo Studies

Molecules, 2019
Colorectal cancer is the third most commonly occurring cancer in men and the second most commonly occurring cancer in women worldwide. We have recently reported that curcuminoid complexes labelled with gallium-68 have demonstrated preferential uptake in ...
Giulia Orteca, Federica Pisaneschi, Sara Rubagotti, Tracy W. Liu, Giacomo Biagiotti, David Piwnica-Worms, Michele Iori, Pier Cesare Capponi, Erika Ferrari, Mattia Asti   +9 more
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source