Results 11 to 20 of about 44,757,379 (245)

Intrinsic gallium-68 labeling of nanoclays for in vivo tracking [PDF]

Journal of Pharmaceutical Analysis
Nian Liu, Tingting Wang, Jian Li, Xinhui Su   +3 more
doaj   +2 more sources

Modern Developments in Bifunctional Chelator Design for Gallium Radiopharmaceuticals

Molecules, 2022
The positron-emitting radionuclide gallium-68 has become increasingly utilised in both preclinical and clinical settings with positron emission tomography (PET).
Patrick R. W. J. Davey, Brett M. Paterson   +1 more
doaj   +1 more source

PET/CT of the Spleen with Gallium-Oxine-Labeled, Heat-Damaged Red Blood Cells: Clinical Experience and Technical Aspects

Diagnostics, 2023
Several scintigraphic techniques have been supplemented or replaced by PET/CT methods because of their superior sensitivity, high resolution, and absolute activity quantification capability. The purpose of this project was the development of a PET tracer
Robert Drescher, Philipp Seifert, Sebastian Gröber, Julia Greiser, Christian Kühnel, Falk Gühne, Martin Freesmeyer   +6 more
doaj   +1 more source

Recovery of Gallium-68 and Zinc from HNO₃-Based Solution by Liquid–Liquid Extraction with Arylamino Phosphonates

Molecules, 2022
The cyclotron production of gallium-68 via the 68Zn(p,n)68Ga nuclear reaction in liquid targets is gaining significant traction in clinics. This work describes (1) the synthesis of new arylamino phosphonates via the Kabachnik–Fields reaction, (2) their ...
Fedor Zhuravlev, Arif Gulzar, Lise Falborg   +2 more
doaj   +1 more source

Radachlorin labeled Gallium-68 Pharmaceutical: a New Theranostic Agent for the Integration of Photodynamic Therapy and Nuclear Imaging [PDF]

مجله علوم و فنون هسته‌ای, 2020
The cyclic tetrapyrrolic compounds, such as porphyrins, play an important role in medical research due to their fundamental role in the body of living beings, the ability to accumulate in various human cancer cells, as well as having distinct physical ...
S.Y. Fazaeli Hoseini Nezhad, F. Yari
doaj   +1 more source

Preparation and Evaluation of [¹⁸F]AlF-NOTA-NOC for PET Imaging of Neuroendocrine Tumors: Comparison to [⁶⁸Ga]Ga-DOTA/NOTA-NOC

Molecules, 2022
Background: The somatostatin receptors 1–5 are overexpressed on neuroendocrine neoplasms and, as such, represent a favorable target for molecular imaging.
Johan Hygum Dam, Niels Langkjær, Christina Baun, Birgitte Brinkmann Olsen, Aaraby Yoheswaran Nielsen, Helge Thisgaard   +5 more
doaj   +1 more source

Synthesis and Physicochemical Properties of Cefepime Derivatives Suitable for Labeling with Gallium-68

Applied Sciences, 2023
Bone and soft tissue infections are potentially life-threatening and require immediate and intensive treatment. However, there is still no single diagnostic method that can reliably confirm or rule out such conditions.
Przemysław Koźmiński, Kinga Żelechowska-Matysiak, Ewa Gniazdowska   +2 more
doaj   +1 more source

Fully Automated Production of [⁶⁸Ga]GaFAPI-46 with Gallium-68 from Cyclotron Using Liquid Targets. [PDF]

Int J Mol Sci, 2023
68Ga-based radiopharmaceuticals are routinely used for PET imaging of multiple types of tumors. Gallium-68 is commonly obtained from 68Ge/68Ga generators, which are limited in the quantity of activity produced.
Fonseca AI, Alves VH, Hrynchak I, Alves F, Abrunhosa AJ.   +4 more
europepmc   +2 more sources

Evaluation of a bispidine‐based chelator for gallium‐68 and of the porphyrin conjugate as PET/PDT theranostic agent [PDF]

, 2020
In this study a bispidine ligand has been applied to the complexation of gallium(III) and radiolabelled with gallium‐68 for the first time. Despite its 5‐coordinate nature, the resulting complex is stable in serum for over two hours, demonstrating a ...
Price, Thomas, Gillet, Raphaël, Boyle, Ross W., Huguette Savoie, Nonat, Aline M., Raphaël Gillet, Gillet, R, Stasiuk, Graeme J., Loïc J. Charbonnière, Steven Y. Yap, Graeme J. Stasiuk, Stasiuk, GJ, Savoie, Huguette, Nonat, A, Thomas W. Price, Yap, Steven, Stasiuk, Graeme, J., Ross W. Boyle, Nonat, Aline, Price, T, Boyle, R, Boyle, Ross, Savoie, H, Charbonnière, Loïc J., Charbonniere, Loic, Stasiuk, Graeme J; id_orcid, Yap, S, Nonat, Aline, M., Charbonnière, L, Yap, Steven Y., Aline M. Nonat   +30 more
core   +2 more sources

Multi-curie production of gallium-68 on a biomedical cyclotron and automated radiolabelling of PSMA-11 and DOTATATE

EJNMMI Radiopharmacy and Chemistry, 2021
Background With increasing clinical demand for gallium-68, commercial germanium-68/gallium-68 ([68Ge]Ge/[68Ga]Ga) generators are incapable of supplying sufficient amounts of the short-lived daughter isotope.
Helge Thisgaard, Joel Kumlin, Niels Langkjær, Jansen Chua, Brian Hook, Mikael Jensen, Amir Kassaian, Stefan Zeisler, Sogol Borjian, Michael Cross, Paul Schaffer, Johan Hygum Dam   +11 more
doaj   +1 more source