Results 151 to 160 of about 2,651 (189)
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Separation of Liquiritin by simulated moving bed chromatography
Journal of Chromatography A, 2007Liquiritin was extracted from the natural product Licorice, and then purified using a three-zone simulated moving bed set up in our laboratory, with a C(18)-bonded silica as the stationary phase and an aqueous solution of ethanol as the mobile phase. The isotherm parameters of Liquiritin and of the only closely eluting impurity were obtained using the ...
Jingxiang, Cong, Bingchang, Lin
exaly +3 more sources
Effect of liquiritin on neuroendocrine‐immune network in menopausal rat model
Phytotherapy Research, 2020AbstractPurposeThe aim of the study was to investigate the effect of liquiritin on neuroendocrine‐immune network in menopausal rat model.MethodsLiquiritin groups were respectively given liquiritin suspension at the dose of 80, 40, and 20 mg/kg, once a day for continuous 30 days after the removal of bilateral ovaries to induce the menopausal rat model ...
Ling Wang, Chun-Feng Zhang, Fei Li
exaly +3 more sources
Involvement of FGF-2 modulation in the antidepressant-like effects of liquiritin in mice
European Journal of Pharmacology, 2020It has been reported that liquiritin produced an antidepressant-like effect in rodents. However, little information is known regarding its antidepressant activity with the regulation of fibroblast growth factor 2 (FGF-2), a protein maintaining development and maturation of the nervous central system.
Litao Yi, Guang-Hui Xu, Ji-Xiao Zhu
exaly +3 more sources
Protective effects of liquiritin on UVB-induced skin damage in SD rats
International Immunopharmacology, 2021Overexposure to ultraviolet B (UVB) rays can cause damage to the skin. Liquiritin has a variety of pharmacological effects, such as anti-inflammatory and antioxidant. In the present study, the effect of liquiritin on UVB irradiated rat skin was investigated.
Xia Zhang, Hanqing Wang, Xiaojuan Gao
exaly +3 more sources
Effect of liquiritin on human intestinal bacteria growth: metabolism and modulation
Biomedical Chromatography, 2014ABSTRACTLicorice is one of the oldest and most frequently used prescribed traditional Chimese medicines. However, the route and metabolites of liquiritin by human intestinal microflora are not well understood and its metabolites may accumulate to exert physiological effects.
Wei, Zhang +4 more
exaly +3 more sources
Liquiritin from Glycyrrhiza uralensis Attenuating Rheumatoid Arthritis via Reducing Inflammation, Suppressing Angiogenesis, and Inhibiting MAPK Signaling Pathway [PDF]
Among the various treatments, induction of synoviocyte apoptosis by natural products during a rheumatoid arthritis (RA) pathological condition can be considered to have vast potential.
Kefeng Zhai +2 more
exaly +2 more sources
Topical liquiritin improves melasma
International Journal of Dermatology, 2000Twenty women with a clinical diagnosis of melasma were treated with liquiritin cream on one side of the face and with a vehicle cream on the other side twice daily for 4 weeks. Patients were advised to avoid sun exposure and/or used topical sunscreen during the entire period of treatment.Inclusion criteria included an age range from 18 to 40 years and ...
M, Amer, M, Metwalli
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Facile optimization for chromatographic separation of liquiritin and liquiritigenin
Journal of Chromatography A, 2013A reversed phase chromatographic system, composed of a stationary phase of C18 silica gel (ODS, 20μm) and a mobile phase of ethanol/water, was used to separate liquiritin and liquiritigenin in the raw material of flavonoids. The linear adsorption isotherm and the equilibrium-dispersive model were adopted to approximatively describe the chromatographic ...
Shaoyan, Wang +3 more
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International Journal of Pharmaceutics, 2021
The purpose of this study was to develop a precursor liposome nano-delivery system for liquiritin (LT) to improve its solubility, oral bioavailability, and efficacy. The characterizations of the particle diameter, zeta potential, polydispersity index (PDI), droplet morphology, drug release in vitro, and oral bioavailability of the prepared LT precursor
Qilong, Wang +8 more
openaire +2 more sources
The purpose of this study was to develop a precursor liposome nano-delivery system for liquiritin (LT) to improve its solubility, oral bioavailability, and efficacy. The characterizations of the particle diameter, zeta potential, polydispersity index (PDI), droplet morphology, drug release in vitro, and oral bioavailability of the prepared LT precursor
Qilong, Wang +8 more
openaire +2 more sources

