Results 1 to 10 of about 32,756 (162)

Effect of hemodialysis on plasma glucose profile and plasma level of liraglutide in patients with type 2 diabetes mellitus and end-stage renal disease: a pilot study. [PDF]

open access: yesPLoS ONE, 2014
The effect of hemodialysis on the plasma glucose profile and liraglutide level after liraglutide injection was investigated in patients with diabetes and end-stage renal disease (ESRD).
Takeshi Osonoi   +6 more
doaj   +5 more sources

Liraglutide alleviates sepsis-associated encephalopathy via attenuating neuronal damage, glial cell activation and mitochondrial dysfunction in a mouse model of sepsis [PDF]

open access: yesEuropean Journal of Medical Research
Objective To explore the relevant mechanisms and principles by which liraglutide alleviates sepsis-associated encephalopathy (SAE) through reducing neuronal injury, glial cell activation and mitochondrial dysfunction.
Xiaoming Li   +6 more
doaj   +2 more sources

Liraglutide-induced structural modulation of the gut microbiota in patients with type 2 diabetes mellitus [PDF]

open access: yesPeerJ, 2021
Accumulating evidence has suggested the importance of gut microbiota in the development of type 2 diabetes mellitus (T2DM). In the present study, 40 patients with T2DM were treated with liraglutide for 4 months. Feces samples and clinical characteristics
Junjie Shang   +9 more
doaj   +2 more sources

Liraglutide; A New Hope for Obese Diabetics [PDF]

open access: yesJLUMHS, 2020
OBJECTIVE: To assess the effectiveness of liraglutide in reducing weight and Glycated haemoglobin (HbA1c) in type 2 diabetic patients. METHODOLOGY: This analytical observational study was conducted at Jinnah medical college hospital Karachi Pakistan ...
Ajeet Kumar   +6 more
doaj   +1 more source

Bolus Injection of Liraglutide Raises Plasma Glucose in Normal Rats by Activating Glucagon-like Peptide 1 Receptor in the Brain

open access: yesPharmaceuticals, 2022
Diabetes is commonly treated with glucagon-like peptide-1 receptor (GLP-1R) agonists including liraglutide and others. However, liraglutide was found to raise plasma glucose levels in normal rats.
Chia-Chen Hsu   +4 more
doaj   +1 more source

Liraglutide Improves the Angiogenic Capability of EPC and Promotes Ischemic Angiogenesis in Mice under Diabetic Conditions through an Nrf2-Dependent Mechanism

open access: yesCells, 2022
The impairment in endothelial progenitor cell (EPC) functions results in dysregulation of vascular homeostasis and dysfunction of the endothelium under diabetic conditions.
Xiaoqing Yan   +16 more
doaj   +1 more source

Liraglutide and Exercise: A Possible Treatment for Obesity?

open access: yesObesities, 2022
(1) Background: Obesity has become an important public health problem worldwide, and its characterization as a chronic disease reflects the impact of a complex and multifactorial condition.
Ana Paula Azevêdo Macêdo   +4 more
doaj   +1 more source

Pharmacokinetics and brain distribution of the therapeutic peptide liraglutide by a novel LC–MS/MS analysis

open access: yesJournal of Analytical Science and Technology, 2023
Liraglutide is a glucagon-like peptide-1 (GLP-1) analog that has been utilized for the treatment of type 2 diabetes mellitus. Liraglutide at a higher dose also shows beneficial effects in weight loss, which prompted its widespread use as an anti-obesity ...
Hyeon Seok Oh   +7 more
doaj   +1 more source

A greater proportion of participants with type 2 diabetes achieve treatment targets with insulin degludec/liraglutide versus insulin glargine 100 units/mL at 26 weeks. DUAL VIII, a randomized trial designed to resemble clinical practice [PDF]

open access: yes, 2020
This report presents the efficacy and safety of insulin degludec/liraglutide (IDegLira) versus insulin glargine 100 units/mL (IGlar U100) as initial injectable therapy at 26 weeks in the 104-week DUAL VIII durability trial (NCT02501161). Participants (N =
Aroda, V. R.   +7 more
core   +1 more source

Liraglutide Activates Glucagon-Like Peptide 1 Receptor to Attenuate Hyperglycemia through Endogenous Beta-Endorphin in Diabetic Rats

open access: yesPharmaceuticals, 2020
Liraglutide, an acylated analog of glucagon-like peptide 1 (GLP-1), could improve glycemic control in diabetes. Moreover, endogenous opioid peptides play a role in blood sugar regulation.
Kai-Chun Cheng   +4 more
doaj   +1 more source

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