Abstract Objective To systematically evaluate and compare the efficacy and safety of three fixed‐ratio combination products—insulin degludec/liraglutide (IDegLira), insulin glargine/lixisenatide (iGlarLixi), and insulin degludec/insulin aspart (IDegAsp)—in patients with type 2 diabetes.
Xiaomei Wang +3 more
wiley +1 more source
Impact of Liraglutide on Insulin Clearance in Patients with Type 2 Diabetes Mellitus: Evidence from a Randomized Controlled Trial. [PDF]
Boelling M, Pu J, Shen J, Retnakaran R.
europepmc +1 more source
In a woman with KCNJ11‐related permanent neonatal diabetes mellitus, incretin‐based therapy enabled insulin discontinuation and maintained glycemic control for more than 5 years, with HbA1c between 6.1% and 6.5% on the lowest semaglutide dose, dose‐dependent improvement in insulin secretion, and an approximately 60% reduction in glibenclamide dose ...
Toshiaki Ohkuma +4 more
wiley +1 more source
Efficacy comparison of dapagliflozin combined with liraglutide versus monotherapy in obese patients with heart failure. [PDF]
Zhou G, Liu A, Hu X, Qi G, Zhang Y.
europepmc +1 more source
Impact of weight‐loss interventions on psoriasis severity: A systematic review and meta‐analysis
Weight‐loss interventions were associated with clinically and statistically significant improvements in psoriasis severity (PASI and PASI 75) and quality of life (DLQI). These findings support the role of weight‐loss interventions as effective adjuncts to medical therapy and their integration into holistic psoriasis care.
Sarah Morrow +6 more
wiley +1 more source
Community Pharmacists' Knowledge and Counseling Competence on GLP-1 Receptor Agonists in Obesity and Type 2 Diabetes Care in Türkiye: A Cross-Sectional Study. [PDF]
Bayram-Ozgur D, Demirtürk E, Sar Y.
europepmc +1 more source
The Role of Oxidative Stress in Periodontitis
Oxidative stress is involved in multiple chemical reactions that take place in different intracellular organelles: mitochondria, rough endoplasmic reticulum, peroxisomes, autophagy, and aging, and can be influenced by exogenous factors: nutrition, physical activity, psychological status, environmental conditions, microbiome, and drugs.
Pedro Bullon +3 more
wiley +1 more source
Emulating the LEADER trial in China: a regulatory science case study on non-interventional research. [PDF]
Zhao J +6 more
europepmc +1 more source
ABSTRACT Next‐generation incretin therapies, including semaglutide and tirzepatide, have transformed obesity and Type 2 diabetes management. However, evidence‐based nutritional strategies to support safe and effective use of these agents remain limited.
Marie Spreckley +2 more
wiley +1 more source
Liraglutide attenuates aluminum chloride-induced Alzheimer's disease in rats by modulating the oxLDL/LPA/LPAR1 pathway. [PDF]
Abo El-Magd NF, Ramadan NM, Eraky SM.
europepmc +1 more source

