Results 91 to 100 of about 13,805 (257)
DCX knockout ferret reveals a neurogenic mechanism in cortical development
Cell ReportsSummary: Lissencephaly is a rare brain malformation for which our understanding remains limited due to the absence of suitable animal models that accurately represent human phenotypes.
Wei Wang +12 more
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bioRxiv, 2018 ‘Tubulinopathies’ are severe human brain malformations associated with mutations in tubulin genes. Despite the identification of many tubulin mutations in patients, we do not understand how these mutations impact the microtubule cytoskeleton, how the ...
Jayne Aiken, J. K. Moore, E. Bates
semanticscholar +1 more source
A case of epigastric heteropagus twinning with other congenital abnormalities in a Chihuahua puppy [PDF]
, 2012 A two-year-old Chihuahua was presented on day 58 of pregnancy due to very marked abdominal distension. A cesarean section was performed and five normal and one clearly abnormal puppy were delivered.
Barrand, KR, Cornillie, Pieter, House, J
core
Methodological advances in imaging intravital axonal transport [PDF]
, 2017 Axonal transport is the active process whereby neurons transport cargoes such as organelles and proteins anterogradely from the cell body to the axon terminal and retrogradely in the opposite direction.
Schiavo, G +3 more
core +5 more sources
Neurobiology of DiseaseProper topographically organized neural connections between the thalamus and the cerebral cortex are mandatory for thalamus function. Thalamocortical (TC) fiber growth begins during the embryonic period and completes by the third trimester of gestation ...
Sheng-Min Huang +4 more
doaj +1 more source
MALFORMATIONS OF CENTRAL NERVOUS SYSTEM: GENERAL ISSUES [PDF]
, 2013 Malformations of the central nervous system (CNS) encompass a heterogeneous group of congenital anomalies that may be isolated or appear as part of a genetic syndrome.
Alongi,A +9 more
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Identification of Alternative Transcription Start Sites that Generate Neuron-Specific nhsl1b Isoform that Regulates Neuron Migration [PDF]
, 2020 Identification of Alternative Transcription Start Sites that Generate Neuron-Specific nhsl1b Isoform that Regulates Neuron Migration Abanoub Bector, Depts. of Biology and Chemistry, with Dr. Sarah Golding, Dept.
Bector, Abanoub
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Haploinsufficiency of DNA damage response genes and their potential influence in human genomic disorders [PDF]
, 2008 Genomic disorders are a clinically diverse group of conditions caused by gain, loss or re-orientation of a genomic region containing dosage-sensitive genes.
O'Driscoll, Mark
core +4 more sources
Characterizing the morbid genome of ciliopathies [PDF]
, 2016 Background Ciliopathies are clinically diverse disorders of the primary cilium. Remarkable progress has been made in understanding the molecular basis of these genetically heterogeneous conditions; however, our knowledge of their morbid genome ...
A Poretti +75 more
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eLife, 2020 Layering has been a long-appreciated feature of higher order mammalian brain structures but the extent to which it plays an instructive role in synaptic specification remains unknown.
James A D'Amour +4 more
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