Results 121 to 130 of about 108,010 (298)

`Electronic Publishing' -- Practice and Experience [PDF]

open access: yes, 1990
Electronic Publishing -- Origination, Dissemination and Design (EP-odd) is an academic journal which publishes refereed papers in the subject area of electronic publishing.
Brailsford, David F.   +2 more
core  

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

The Philippine Journal of Development: Its Beginning and Evolution [PDF]

open access: yes
This paper traces the beginning and evolution of the Philippine Journal of Development--from its conception as a technical journal of the National Economic and Development Authority (NEDA), its transfer of management to the Philippine Institute for ...
Liguton, Jennifer P.T.
core  

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

In brief: Men in black: the impact of new contracts on football referees' performance [PDF]

open access: yes
In the 2001/02 English football season, referees of Premier League matches were paid a salary for the first time. Alex Bryson and colleagues investigate the impact on their performance.salary contracts, performance relate ...
Alex Bryson
core  

Safeguarding Old and New Journal Tables for the VO: Status for Extragalactic and Radio Data

open access: yes, 2009
Independent of established data centers, and partly for my own research, since 1989 I have been collecting the tabular data from over 2600 articles concerned with radio sources and extragalactic objects in general. Optical character recognition (OCR) was
Andernach, Heinz
core   +2 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Acknowledgements for reviewers 2015-2016

open access: yesMaderas: Ciencia y Tecnología, 2016
The Scientific-Editor and Technical-Editor of Maderas-Cienc Tecnol are grateful to the reviewers for their assistance as referees into the peer review processes of the journal.The quality of the scientific contents of the Maderas-Cienc Tecnol depends on ...
Maderas-Cienc Tecnol
doaj  

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