Results 41 to 50 of about 731,688 (334)

Aesthetics and literature : a problematic relation? [PDF]

, 2007
The paper argues that there is a proper place for literature within aesthetics but that care must be taken in identifying just what the relation is. In characterising aesthetic pleasure associated with literature it is all too easy to fall into reductive
F. Kermode, F. Sibley, H. Bloom, M. Budd, M. Rowe, N. Carroll, P. Bourdieu, P. Kivy, P. V. Lamarque, P. V. Lamarque, P. V. Lamarque, P. V. Lamarque, P. V. Lamarque, P. V. Lamarque, P. V. Lamarque, Peter Lamarque, R. Barthes, R. Rorty, R. Stecker, S. Feagin, S. H. Olsen, T. Eagleton, T. Greene, W. Peer van   +23 more
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Helen Oyeyemi and Border Identities: Contesting Western Representations of Immigrants through Transnational Literature [PDF]

, 2018
Oyeyemi is a Nigerian-British writer whose writing, like other immigrant authors\u27, participates in a dialogue about and contestation of essentialized immigrant and ethnic identities that are a result of global and local processes. Her writing produces
Mills, Susanna L.
core   +1 more source

Amores de Abat-jour: A cena teatral brasileira e a escrita de mulheres nos anos vinte [PDF]

, 2001
Recently many researchers are interested in rescuing works and names excluded from the Brazilian literary canon. Among these "forgotten" names are several women playwrights, among them Maria Eugênia Celso.
Costa Bezerra, Kátia da
core   +2 more sources

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

American Literature for Millennial and Centennial Undergraduates: Reflections upon an Eclectic Teaching Model

Tejuelo: Didáctica de la Lengua y la Literatura, 2020
The question of the canon in American Literature classroom of Spanish universities is influenced by the ‘Cultural Wars’ that, since the 1990s, have been fought in the United States between the supporters of maintaining a tradition close to the dominant ...
Julio Cañero Serrano
doaj   +1 more source

Postprint Copy of Years of Teaching Dangerously: Interfacing Thomas Cromwell in Canon and Fandom, Michael Drayton, “W.S.,” and Hilary Mantel [PDF]

, 2016
When Sir Thomas Bodley founded the Bodleian Library, he sought to keep “baggage books,” “riff-raff books,” and distasteful literature off the shelves. The question of keeping literature in or out of a library or canon is never simply about literature; it
Laurie Ringer
core   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source