Results 41 to 50 of about 1,954 (264)

Etnografias imaginárias: literatura, teoria e cânone por Pozuelo Yvancos

Caligrama: Revista de Estudos Românicos, 2011
Palavras-chave: José María Pozuelo Yvancos; Teoría del canon y literatura española; crítica literária.Keywords: José María Pozuelo Yvancos; Teoría del canon y literatura española; literary criticism.
Sabrina Sedlmayer, Gabriel Schünemann, Janine Rocha, Josué Borges de Araújo Godinho, Luciano Danilo Silva, Vinícius Ribeiro Pimentel, Yara Augusto   +6 more
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

Gestación y revisión canónica: El caso de la literatura norteamericana

Revista Chilena de Literatura, 2016
A partir de una reflexión acerca de los sentidos contradictorios del concepto de canon literario, este trabajo entrega una visión de la polémica que los intentos de revisión y reformulación del canon e historia literaria de los Estados Unidos han ...
Irene Rostagno Eytel
doaj  

Identity Politics and the Literary Canon: Sándor Márai’s Place in the Hungarian Literary Canon

Colloquia
The paper examines the place of Sándor Márai (1900–1989) in the Hungarian literary canon, specifically, in the context of the discussion on the canon and national identity in the former Eastern Bloc countries after 1989. It draws on the understanding of the canon as a tool used to propagate a certain model of identity within a given society and shows ...
openaire   +2 more sources

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Między kanonem literackim 
a kulturą zwielokrotnioną

Postscriptum Polonistyczne, 2020
Contemporary cultural changes force Polish literary critics to constantly change their views on literature. Traditional literary canon is prone to stagnation and inertia, but multiculturalism may lead to a dangerous melting in the multiplied maze of ...
Maria Delaperrière
doaj  

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Manifestări ale autismului naţionalofob în presa postdecembristă: de la „identităţile interşanjabile” la „negustorii de iluzii” [PDF]

Revista de Istorie și Teorie Literară, 2012
Within the post-December period, the Romanian cultural background has witnessed the conflictive phenomenon of critical revision focusing on the (in)validation of the literary canon by means of two dichotomic approaches: the ethicist one looking for the ...
Nicoleta Ifrim
doaj  

Stephen King and the Contemporary Literary Canon: Strategies of Institutionalization and Legitimation [PDF]

Литература двух Америк
This article analyzes the institutional mechanisms through which popular literature becomes part of the contemporary literary canon. Using the case of Stephen King’s transformation from a marginal horror writer to a recognized figure in the academic and ...
Nataliya V. Kireeva
doaj   +1 more source