Results 91 to 100 of about 827,412 (367)
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Guns end dreams: linguistic choices as trauma narrations in Baki and Adedoyin’s End sars rhythms
Cogent Arts & HumanitiesThis paper examines the poetic presentation of the October 2020 #EndSARS protest as traumatic narrations in Baki and Adedoyin’s End sars rhythms. Drawing on insights from literary trauma theory and the concept of trauma discourse, data were purposively ...
God’sgift Ogban Uwen, Edem Ekpo Ene
doaj +1 more source
Imagining Village Life in Zambian Fiction [PDF]
, 2005 The dualism between the urban and the rural space, and between the systems of social relationships obtaining in each sphere, has proved to be an enduring source of inspiration to African fictional writers since the inception of the genre. Many studies of
Macola, Giacomo
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INTERPRETATION OF ILLUSTRATIONS IN LITERARY READING LESSONS WHEN STUDYING N. ABRAMTSEVA'S FAIRY TALES [PDF]
, 2020 Natalya V. Kulakova +4 more
openalex +1 more source
Repetitive Research: A Conceptual Space and Terminology of Replication, Reproduction, Re-Implementation, Re-Analysis, and Re-Use in Computational Literary Studies [PDF]
, 2023 Christof Schöch
openalex +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
English Bards and Unknown Reviewers: a Stylometric Analysis of Thomas Moore and the Christabel Review [PDF]
, 2015 Fraught relations between authors and critics are a commonplace of literary history. The particular case that we discuss in this article, a negative review of Samuel Taylor Coleridge's Christabel (1816), has an additional point of interest beyond the ...
Benatti, Francesca, Tonra, Justin
core +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Agaat's Law. Reflections on Law and Literature with Reference to Marlene Van Niekerk's novel Agaat [PDF]
, 2009 This essay explores the relation between law and literature from the literary Marxist position that Jean-Luc Nancy develops in his work La Communauté Désoeuvrée.
Van der Walt, J.
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