Results 101 to 110 of about 118,624 (316)
For a Reappreciation of the Literary in Literary Studies: Poetic Thinking
Interlitteraria, 2020 As a literary scholar based in German Studies outside of Germany, I am confronted with German being considered a minor subject matter. There are evidently clear differences between the German departments within German-speaking countries and abroad. The latter are shrinking considerably almost everywhere and need to focus on few aspects, often related ...
openaire +3 more sources
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
In the Cracks between Narration and Experience : Narrative Dissonance in Literary Journalism
In fiction, narrative dissonance highlights a narrator’s retrospective perspective at the expense of a character’s perspective. In literary journalism/reportage, narrative dissonance presents a method for questioning any absolute truth in a specific ...
Aare, Cecilia
core +2 more sources
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
Where literary studies is, and what it does
, 2013 In recent years, both in the United States and the United Kingdom, there has been a good deal of talk about the state of Humanities, with the dominant view that crisis, if not here already, will soon be upon us.
Uhlmann, Anthony (R8739)
core
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Studies in Linguistics and Language EducationIn this paper we examine the non-resolution of questions under discussion (QUDs) in political interviews, using Roberts’s (2012) QUD framework and the annotation methodology developed by Riester et al. (2018).
Raoul Schubert, René Nicolas
doaj
Guns end dreams: linguistic choices as trauma narrations in Baki and Adedoyin’s End sars rhythms
Cogent Arts & HumanitiesThis paper examines the poetic presentation of the October 2020 #EndSARS protest as traumatic narrations in Baki and Adedoyin’s End sars rhythms. Drawing on insights from literary trauma theory and the concept of trauma discourse, data were purposively ...
God’sgift Ogban Uwen, Edem Ekpo Ene
doaj +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source