Results 81 to 90 of about 627,418 (357)
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Humor production in children’s narratives in Spanish
Calidoscópio, 2017 The aim of this paper is to analyze children’s production of humor from a linguistic perspective. Our research focuses on linguistic aspects of humor production and appreciation analyzed through a corpus of 148 narratives in Spanish about the same ...
Leonor Ruiz-Gurillo
doaj +3 more sources
Sign Systems Studies, 2016 The paper explores theoretical foundations of the frame from two semiotic perspectives: that of the Saussurean dyadic sign dominant in the European tradition and that of the triadic sign of the Peircean/American descent.
Wojciech Kalaga
doaj +1 more source
On context and literary theory [PDF]
, 2018 In this paper, we analyze the importance of context in modern literary theory and the relevance of context within literary study. After the fall of formalism and structuralism, which emphasized the autonomy of the text and the specificity of literature ...
Jiménez, Mauro
core +1 more source
Toward an innovative poetics : Wang Changling on Yi 意 and literary creation
, 2017 This article reveals the coherent theory of literary creation hidden within the multivalence of the term yi in Wang Changling\u27s (ca. 698–ca. 756) writings on poetry.
CAI, Zongqi
core +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
On McGann's "philological conscience"
MatLit, 2016 Book review of Jerome McGann, A New Republic of Letters: Memory and Scholarship in the Age of Digital Reproduction, Cambridge, MA: Harvard University Press, 2014, 238 pp. ISBN: 978-0-674-72869-1.
Brito, Matheus de
doaj +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Games and literary theory conference, 2013 : conference review [PDF]
, 2014 The Department of English of the University of Malta collaborated with the Institute of Digital Games (University of Malta) to hold the First International Conference on Games and Literary Theory.
Farrugia, James, Micallef, Jeffrey
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source