Results 131 to 140 of about 14,134,939 (334)

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

open access: yesMolecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad   +13 more
wiley   +1 more source

CitNetExplorer: A new software tool for analyzing and visualizing citation networks [PDF]

open access: yesarXiv, 2014
We present CitNetExplorer, a new software tool for analyzing and visualizing citation networks of scientific publications. CitNetExplorer can for instance be used to study the development of a research field, to delineate the literature on a research topic, and to support literature reviewing.
arxiv  

The Chronicles of Jeremiah Goldswin Albany Settler of 1820 [PDF]

open access: yes, 1946
https://commons.und.edu/settler-literature/1200/thumbnail ...
Long, Una
core   +1 more source

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

open access: yesMolecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran   +16 more
wiley   +1 more source

Winter 2019: Department of Literature and Modern Languages Newsletter [PDF]

open access: yes, 2019
https://nsuworks.nova.edu/cahss_dlml_newsletter/1000/thumbnail ...
Department of Literature and Modern Languages
core   +1 more source

Impact of molecular diagnostics and targeted cancer therapy on patient outcomes (MODIFY): a retrospective study of the implementation of precision oncology

open access: yesMolecular Oncology, EarlyView.
The authors conducted a retrospective study of 94 patients with advanced cancer who underwent next‐generation sequencing (NGS) gene panel analysis and received targeted treatments when applicable. Results further support evidence indicating that molecular profiling provides clinical benefit.
Michaël Dang   +3 more
wiley   +1 more source

NLP-Powered Repository and Search Engine for Academic Papers: A Case Study on Cyber Risk Literature with CyLit [PDF]

open access: yesarXiv
As the body of academic literature continues to grow, researchers face increasing difficulties in effectively searching for relevant resources. Existing databases and search engines often fall short of providing a comprehensive and contextually relevant collection of academic literature.
arxiv  

Controversy about quantum time decay [PDF]

open access: yesarXiv, 2001
In the recent physics literature there have appeared contradictory statements concerning the behaviour of scattering solutions of the 3-dimensional Schroedinger equation at large times. We clarify the situation and point out that the issue was rigorously resolved in the mathematics literature.
arxiv  

KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells

open access: yesMolecular Oncology, EarlyView.
We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock   +10 more
wiley   +1 more source

What Is in the Literature

open access: yesJournal of Clinical Neuromuscular Disease, 2017
Abstract This installment of what is in the literature is on amyotrophic lateral sclerosis (ALS). The pathophysiology of ALS remains open and the role of genes, a foothold into pathophysiology, but there are >22 genes identified, and the mechanisms are not known for any.
openaire   +12 more sources

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