Results 31 to 40 of about 202,091 (266)

Mapping the circle of Trolard: A holistic view of its role in neurosurgical practice, anatomical perspectives and clinical applications

Brain and Spine
Introduction: An anatomical structure that resembles the circle of Willis, the circle of Trolard is generated in the basal cistern and travels around the midbrain in a roundabout manner, passing adjacent to the lateral side of the cerebral peduncle ...
Oday Atallah, Ahmed Muthana, Vivek Sanker, Omar Wawi, Samer S. Hoz   +4 more
doaj   +1 more source

Dialogue between Language and Literature: A dialogical analysis of Gloria Anzaldúa’s El Sonavabitche and its implications

Calidoscópio, 2016
This article aims at discussing the role linguistic studies play in literary studies based on the theoretical framework of the Circle (Bakhtin, Voloshinov, and Medvedev) and the implications in undergraduate English Language Teacher Education Programs of
Orison Marden Bandeira de Melo Junior
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Literature Circles Strategy as a Support for EFL Students’ Reading Comprehension Skills and Motivation

مجلة الآداب
The current study aims to explore the impact of using literature circles strategy on supporting EFL college students ‘reading comprehension skills and motivation towards reading.
Zainab Jawad
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Are the distributions of variations of circle of Willis different in different populations? – Results of an anatomical study and review of literature

BMC Neurology, 2006
Background Previous studies have proposed correlation between variants of the cerebral arterial circle (also known as circle of Willis) and some cerebrovascular diseases.
Nazparvar Bashir, Ghodsi Mohammad, Ansari Saeed, Dadmehr Majid, Eftekhar Behzad, Ketabchi Ebrahim   +5 more
doaj   +1 more source

The Bakhtin Circle’s dialog in Vietnam

Humanities & Social Sciences Communications, 2021
In this article, we use Jacques Derrida’s deconstructive method to study the influence of Mikhail Bakhtin in Vietnam in the 1990s and 2000s. By using evaluations of Bakhtin by researchers in Vietnam and around the world, we argue that he is not the only ...
Le Huy Bac, Dao Thi Thu Hang, Le Nguyen Phuong   +2 more
doaj   +1 more source