Results 41 to 50 of about 1,325,721 (304)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

An Interview About Circle Dancing [PDF]

open access: yes, 2009
The respondent discusses local circle dancing.The fifty one audio and nine video files in this collection include: villages’ life stories, circle-dancing songs and performance, local history, folk tales, and interviews from Siyuewu Village, Puxi ...
G.yu lha
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Literature Circles Strategy as a Support for EFL Students’ Reading Comprehension Skills and Motivation

open access: yesمجلة الآداب
The current study aims to explore the impact of using literature circles strategy on supporting EFL college students ‘reading comprehension skills and motivation towards reading.
Zainab Jawad
doaj   +1 more source

An Interview Recalling an Argument [PDF]

open access: yes, 2009
The respondent recalls an argument with a village woman.The fifty one audio and nine video files in this collection include: villages’ life stories, circle-dancing songs and performance, local history, folk tales, and interviews from Siyuewu Village ...
G.yu lha
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

The Bakhtin Circle’s dialog in Vietnam

open access: yesHumanities & Social Sciences Communications, 2021
In this article, we use Jacques Derrida’s deconstructive method to study the influence of Mikhail Bakhtin in Vietnam in the 1990s and 2000s. By using evaluations of Bakhtin by researchers in Vietnam and around the world, we argue that he is not the only ...
Le Huy Bac   +2 more
doaj   +1 more source

Village History 1 [PDF]

open access: yes, 2010
Zhangs skyong tells village history concerning a demon which almost destroyed the village.The fifty one audio and nine video files in this collection include: villages’ life stories, circle-dancing songs and performance, local history, folk tales, and ...
G.yu lha
core  

Shared inputs, entrainment, and desynchrony in elliptic bursters: from slow passage to discontinuous circle maps [PDF]

open access: yes, 2011
What input signals will lead to synchrony vs. desynchrony in a group of biological oscillators? This question connects with both classical dynamical systems analyses of entrainment and phase locking and with emerging studies of stimulation patterns for ...
Lajoie, Guillaume, Shea-Brown, Eric
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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