Results 51 to 60 of about 202,091 (266)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Monopole quivers and new 3D N=2 dualities
Nuclear Physics B, 2017 We present a new family of dualities for three-dimensional gauge theories, motivated by the brane realization of the reduction of four-dimensional dualities on a circle. This family can be understood as a generalization of Aharony duality to quiver gauge
Antonio Amariti +2 more
doaj +1 more source
EFFECTIVENESS OF LITERATURE CIRCLES ON STUDENTS’ READING COMPREHENSION
IJOLTL: Indonesian Journal of Language Teaching and Linguistics, 2016 This study reports an experimental study to see the effect of literatures circles to improve reading comprehension of English department students of State Islamic Institute (IAIN) of Samarinda. A quasi experimental research using nonrandomized control group pretest-posttest design was conducted to see effectiveness of literature circles on students ...
openaire +2 more sources
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Autopsy and Case Reports, 2011 Anatomic variations and anomalies in the arteries from the circle of Willis or the heart are common, sometimes even more common than the classic morphology.
David Gonçalves Nordon +3 more
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Phenomenology in nursing research: reflection based on Heidegger’s hermeneutics
Escola Anna NeryObjective: To reflect on the use of phenomenological analysis in nursing research through the hermeneutical circle of Martin Heidegger. Method: Theoretical reflection based on Martin Heidegger’s concepts through literature review.
Raúl Fernando Guerrero-Castañeda +2 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Efekt przełomu, czyli czy rozmowy o kanonie mają sens
Annales Universitatis Paedagogicae Cracoviensis. Studia Poetica, 2014 The effect of a breakthrough, or whether talking about the canon makes sense The article discusses the existence and functioning of the notion of canon in the social consciousness after 1989 in the context of Polish prose of the last twenty years.
Iwona Pięta
doaj
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source