Results 61 to 70 of about 202,091 (266)

The “angle” method of calculating glenoid bone loss: a validation study and review of current methods

JSES International
Hypothesis/Background: This study compares our “angle” method to the ''best-fit circle'' method and examines existing literature on glenoid bone loss measurement.
Lewis L. Shi, MD, James S. MacLeod, MD, Nicholas H. Maassen, MD, Marcus Allen, BA   +3 more
doaj   +1 more source

Names in the Films of R. W. Fassbinder

Names, 1993
The films of R.W. Fassbinder employ character names which are different from character-naming practices in literature. Fassbinder often uses an actor's personal name or a variant as a basis for naming the character.
Russell E. Brown
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Community Life Circle, Neighbourly Interaction, and Social Cohesion: Does Community Space Use Foster Stronger Communities?

Land
Neighbourhood social cohesion has emerged as a prominent concern in urban governance worldwide. As the primary domain of residents’ daily activities, the community life circle contributes to neighbourly interaction and social cohesion.
Min Jiang, Jiaqi Hu, Xiaofeng Gao
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

PENGEMBANGAN MODEL LINGKAR SASTRA DALAM PEMBELAJARAN APRESIASI CERITA PENDEK BERMUATAN NILAI-NILAI PENDIDIKAN KARAKTER PESERTA DIDIK SMP/ MTs

Seloka: Jurnal Pendidikan Bahasa dan Sastra Indonesia, 2014
Keterampilan mengapresiasi cerita pendek sangat penting dikuasai oleh peserta didik. Kenyataannya keterampilan ini belum dikuasai secara maksimal. Oleh karena itu, perlu dikembangkan sebuah model pembelajaran apresiasi cerpen.
Erni Hidayati
doaj  

ІСААК МАЗЕПА В ДЕРЖАВОТВОРЕННІ В УНР ДОБИ ДИРЕКТОРІЇ [PDF]

Storìnki Istorìï, 2012
In the article on the basis of wide circle of the special literature and unpublished sources the contribution of Isaаk Mazepa into the state construction of Ukraine during the period of Directory UPR is considered.
В. Г. Гаврик
doaj  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source