Results 101 to 110 of about 8,668,591 (340)

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Lexico-semantic processing in individuals with Alzheimer’s disease: Evidence from picture naming task in Iranian Azerbaijani Turkish-Persian bilinguals [PDF]

نشریه پژوهش‌های زبان‌شناسی
Adopting a linguistic approach to the pathology of the mind on bilinguals afflicted with aphasia caused by Alzheimer's disease (AD) has given rise to a wide array of interdisciplinary research in recent years. However, bilinguals’ language impairments in
Maryam Pirzadeh, Ramin Golshaie, Mohammad Momenian   +2 more
doaj   +1 more source

The forgotten first: John MacCormick's 'Dùn-Àluinn' [PDF]

, 2006
The first Gaelic novel, John MacCormick's Dùn-Àluinn, no an t-Oighre 'na Dhìobarach, was serialised in the People's Journal in 1910 before being published in its entirety in 1912.
Kidd, S.M.
core  

Examining the Effect of the Ratio of Biomedical Domain to General Domain Data in Corpus in Biomedical Literature Mining [PDF]

, 2021
Ziheng Zhang, Feng Han, Hongjian Zhang, Tomohiro Aoki, Katsuhiko Ogasawara   +4 more
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Value Perception of the Chronotope in the Author’s Discourse (Based on the Works of Kazakh Authors)

Open Cultural Studies
The relevance of the study is due to the increased interest of researchers in the study of the chronotope category in recent decades, and the lack of a unified approach to the analysis of the chronotope in the scientific community.
Zhiyenalina Aizhan, Anishchenko Olga, Zharkynbekova Sholpan   +2 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Global and Local Attention Processing in Depressed Mood [PDF]

Journal of Kerman University of Medical Sciences, 2017
Background: Attention impairments are the hallmark feature of subclinical depression. The present study used Navon task to compare the allocation of attention to the local and global stimuli in depressed and nondepressed participants. Method: The primary
Samaneh Mohammadi-Nasab, Masoud Fazilat-Pour, Abbas Rahmati   +2 more
doaj  

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Present knowledge of the Entomofauna of the Maltese Islands [PDF]

, 2000
The Maltese Islands' strategic position in the centre of the Mediterranean basin and in between the Siculo Tunisian sill, always encouraged a number of foreign naturalists to visit and study their local entomofauna.
Mifsud, David
core