Results 51 to 60 of about 8,550,777 (369)

Molecular insights into the modulation of the 5HT2A receptor by serotonin, psilocin, and the G protein subunit Gqα

open access: yesFEBS Letters, Volume 599, Issue 6, Page 876-891, March 2025.
We explore 5HT2A receptor activation, a key target for psychedelic drugs, using molecular dynamics simulations. Without Gqα, the active receptor collapses to an inactive conformation, underscoring the G‐protein's role. Discovery of an intermediate “partially‐open” state and the higher affinity of ligands to the orthosteric binding site provides ...
Niklas Viohl   +2 more
wiley   +1 more source

Ethnic minority business in the uk: a review of research and policy development [PDF]

open access: yes, 2008
Part of a series produced to support a ESRC/CRE/DTI/emda workshop on ethnic minority entrepreneurship. This paper comprised a review of research literature on ethnic minority enterprise and an overview of UK policy ...
Jones, T, Ram, M
core   +1 more source

Interaction between bacterial phytochromes Agp1 and Agp2 of Agrobacterium fabrum by fluorescence resonance energy transfer and docking studies

open access: yesFEBS Letters, Volume 599, Issue 6, Page 848-865, March 2025.
The interaction between Agrobacterium fabrum phytochromes Agp1 and Agp2 was studied using FRET. Full‐length and truncated proteins with varied label positions provided spatial insights, narrowing down from many docking models to three. These models explain Agp2's reduction in Agp1 autophosphorylation, with Arg83 of Agp2 specifically evolved to interact
Afaf El Kurdi   +7 more
wiley   +1 more source

Recycled Rubber as an Aggregate Replacement in Self-Compacting Concrete—Literature Overview

open access: yesMaterials, 2018
In the past few decades, due to the exponential increase of the world’s population, the number of discarded waste tires has become a serious ecological and environmental problem. Decomposition of waste tire rubber can take longer than 50 years, and every
Robert Bušić   +3 more
semanticscholar   +1 more source

Mechanism of thermal decomposition of poly(ether ether ketone) (PEEK) from a review of decomposition studies [PDF]

open access: yes, 2010
A review of the literature on the flammability and decomposition of poly(oxy-1,4-phenyleneoxy-1,4-phenylenecarbonyl-1,4-phenylene) (PEEK) is presented. This paper provides an overview of the flammability of PEEK and its decomposition mechanisms. Based on
Flath, Dianne   +5 more
core   +1 more source

Immunoregulatory mechanisms of the arachidonic acid pathway in cancer

open access: yesFEBS Letters, Volume 599, Issue 7, Page 927-951, April 2025.
The central role of the arachidonic acid (AA) pathway in anticancer immunity. Enzymes and metabolites of the AA pathway can play both immunosuppressive and immunostimulatory roles in the tumor microenvironment. Therefore, their tailored targeting could be beneficial as a standalone therapy or in combination with current cancer immunotherapy.
Maria Tredicine   +3 more
wiley   +1 more source

Spectrum Analysis of LTI Continuous-Time Systems With Constant Delays: A Literature Overview of Some Recent Results

open access: yesIEEE Access, 2018
In recent decades, increasingly intensive research attention has been given to dynamical systems containing delays and those affected by the after-effect phenomenon.
L. Pekař, Qingbin Gao
semanticscholar   +1 more source

Genetic epidemiology literature in Europe an overview [PDF]

open access: yesThe European Journal of Public Health, 2007
Genetic epidemiology deals with the aetiology, distribution and control of disease in groups of relatives, and with inherited causes of disease in populations. The main goal of this overview, part of the collaborative study SPHERE (Strengthening Public Health Research in Europe) was to have an up-to-date, detailed summary of the available information ...
Ádány, Róza, Pocsai, Zsuzsanna
openaire   +3 more sources

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