Results 111 to 120 of about 58,443,833 (259)

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Data protection and the health research regulations: finding a way forward: report and recommendations [PDF]

, 2019
This report presents the proceedings of the Irish Health Research Forum meeting on May 16th 2019 which focused on data protection and health research legislation, in the context of the Health Research ...
Medical Research Charities Group
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Aboriginal and Torres Strait Islander art economies project: literature review [PDF]

, 2013
Executive summary: This literature review surveys writing about the Aboriginal and Torres Strait Islander art and craft sector of remote Australia. The review has been compiled as a foundational text for the ‘Aboriginal and Torres Strait Islander Art ...
Lisa Stefanoff, Woodhead, A., Tim Acker, Acker, Tim, Stefanoff, L., Alice Woodhead   +5 more
core   +1 more source

Assessing the impact of research on policy: a literature review

, 2009
Understanding the impact of research on policy is a vital, and often overlooked, element of policy-making. A systematic literature review was conducted to examine methods for evaluating the impact of research on policy outcomes.
Boaz, Annette, Boaz, A., Fitzpatrick, S., Shaw, B., Fitzpatrick, Siobhan, Shaw, Ben   +5 more
core   +1 more source

Mesenchymal Stem Cells (MSCs) as a Potential Therapeutic Strategy in COVID-19 Patients: Literature Research. [PDF]

Front Cell Dev Biol, 2020
Coelho A, Alvites RD, Branquinho MV, Guerreiro SG, Maurício AC.   +4 more
europepmc   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

The role of “Hadih Maja” as an Acehnese oral tradition in supporting UN Sustainable Development Goals (SDGs) 2030 agendas: an eco-criticism analysis

Cogent Social Sciences
Issues on climate change, global warming, renewable energy, food security, forest conservation, sustainable marine life resources, and protecting wildlife are becoming central issues for the world community these days.
Iskandar Syahputera, Sastri Sunarti, Tugas Tri Wahyono, Zulkarnain Yani, Yustina Hastrini Nurwanti, Lina Herlinawati, Ninawati Syahrul, Musfeptial Musfeptial   +7 more
doaj   +1 more source

The sustainable development of mathematics subject: An empirical analysis based on the academic attention and literature research.

Heliyon, 2023
Zhao Y, Li J, Liu K.
europepmc   +1 more source