The issue of off-season training in American football (review study)
The aim of the present paper was to use literature research to compile knowledge and information from professional and scientific articles or publications dealing with the issue and to create a survey study on the issue of off-season training in American
Aleš Kaplan, Ondřej Mička
doaj
И. С. Галкин 90 [I. S. Galkin 90] [PDF]
Valerij Maksimov +4 more
doaj +1 more source
Occidentalism: Conceptual Formation, Intellectual Dimensions, Poetics, and Significance
Abstract: Occidentalism is a way of understanding the world that allows non-Western societies to question how the West has shaped global narratives.
Muhammad Yousuf
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
A Fluid Border: The River Tamar and Constructed Difference in Travel Writing of Cornwall
The Tamar is a relatively modest river. With a length of just 61 miles, and an average discharge at the upper tidal limit of just 807 cubic feet per second, it is dwarfed by other British rivers such as the Severn and the Thames.
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Research Impact and Sustainability in Education: A Conceptual Literature Review
Research sustainability and research impact are closely related concepts, both referring to the importance of extending research projects’ outcomes, changes or benefits beyond their period of implementation.
Ricardo Torres +2 more
doaj +1 more source

