Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
The Victorian Illustrating of Shakespeare’s Women: Metal Engraving [PDF]
This article seeks to examine the illustrated editions of Shakespeare's plays, whose images were printed by the use of metal engraving, in order to find the most determining factors that affect the way of understanding the female characters in the play ...
Afrooz Khaleghi +2 more
doaj +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
An analysis of the phonological system of Dayak Bentian language in East Kalimantan, Indonesia
This research discusses the phonological description of the Dayak Bentian (DB) language, its comparison with other Dayak languages, and its relation to Austronesian language patterns, as part of language documentation.
Andi Indah Yulianti +5 more
doaj +1 more source
Background A review of literature published a decade ago noted a significant increase in empirical papers across nine bioethics journals. This study provides an update on the presence of empirical papers in the same nine journals.
Tenzin Wangmo +5 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Grey literature : the challenges for an increasingly important body of research literature
Grey literature both exemplifies and magnifies the many problems faced by the world's research libraries, which must cope with a rising tide of publications, whether traditional or otherwise, and with the growing expectations of their users and funders ...
Simpson, Donald B. (CRL) +1 more
core
Два первых коми словаря, изданные в Коми крае в начале XX века [The First Two Komi Dictionaries, Published in the Komi Region at the Beginning of the XX Century] [PDF]
The paper provides brief biographies of the compilers of the first printed dictionaries of the Komi language, Andrey Andreevich Tsember and Nikolay Aleksandrovich Shakhov. Their goals and procedures in compiling the dictionaries, their materials, methods
Jevgenij Cypanov, Galina Punegova
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source

