Results 41 to 50 of about 7,743 (185)

Pharmacokinetics and Ex Vivo Activity of 7-Methylxanthine, an Inhibitor of Monosodium Urate Crystallization

Biomedicines
Background/Objectives: 7-Methylxanthine (7-MX) is a naturally occurring metabolite of caffeine and theobromine that can inhibit the crystallization of monosodium urate (MSU) and may be useful for the prevention or treatment of gout.
Miguel D. Ferrer, Jaume Dietrich, Bernat Isern, Maria del Mar Pérez-Ferrer, Joan Albertí, Félix Grases, Antònia Costa-Bauzà   +6 more
doaj   +1 more source

Treatment of recurrent renal transplant lithiasis: analysis of our experience and review of the relevant literature

BMC Nephrology, 2020
Background Renal transplant lithiasis is a rather unusual disease, and the recurrence of lithiasis presents a challenging situation. Methods We retrospectively analyzed the medical history of one patient who suffered renal transplant lithiasis twice ...
Xiaohang Li, Baifeng Li, Yiman Meng, Lei Yang, Gang Wu, Hongwei Jing, Jianbin Bi, Jialin Zhang   +7 more
doaj   +1 more source

Bladder Stone Secondary to Migration of an Intrauterine Device: A Case Report

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Intravesical migration of intrauterine devices (IUDs) is an uncommon complication that may lead to recurrent urinary tract infections, lower urinary tract symptoms, and bladder stone formation. Diagnosis requires high clinical suspicion and confirmation through imaging and cystoscopy.
Mario Arturo Martin‐Dorantes, Erick Antonio Rochel‐Perez, Michel Alfredo Bastarrachea‐Solis, Juan Pablo Flores‐Tapia, Ashley Yael Sotelo‐Casas, Nina Méndez‐Domínguez   +5 more
wiley   +1 more source

Apolipoproteína A1 e litíase biliar na cirrose hepática.

Acta Médica Portuguesa, 1996
A prospective study was performed in 67 male patients with cirrhosis, admitted in our Department during one year. Biliary lithiasis was found in 37% of patients.
J Baranda, P Ministro, P Amaro, A Rosa, I Pimenta, A Donato, D De Freitas   +6 more
doaj   +1 more source

Effect of Phytate (InsP6) and Other Inositol-Phosphates (InsP5, InsP4, InsP3, InsP2) on Crystallization of Calcium Oxalate, Brushite, and Hydroxyapatite

Biomolecules, 2023
Pathological calcifications may consist of calcium oxalate (CaOx), hydroxyapatite (HAP), and brushite (BRU). The objective of this study was to evaluate the effect of phytate (inositol hexakisphosphate, InsP6), InsP6 hydrolysates, and individual lower ...
Paula Calvó, Antònia Costa-Bauza, Felix Grases   +2 more
doaj   +1 more source

Weaning from ketogenic diet therapy in children with epilepsy: Insights from a retrospective study

Epilepsia, Volume 67, Issue 4, Page 1817-1826, April 2026.
Abstract Objective This study was undertaken to describe weaning practices following ketogenic diet therapy (KDT) in children with epilepsy and to identify clinical factors associated with seizure exacerbation or antiseizure medication adjustments during or after weaning from KDT.
Noémie Donnard, Blandine Dozières‐Puyravel, Katia Geraldes, Céline Perrot, Virginie Quéméner, Estelle Goujon, Pierre Truchy, Hala Nasser, François‐Xavier Mauvais, Marion Danse, Stéphane Auvin   +10 more
wiley   +1 more source

Evidence and Equity Gaps in Clinical Care of Chronic Lymphocytic Leukaemia in Portugal: A Real‐World, Multicentre, Cohort Study

eJHaem, Volume 7, Issue 2, April 2026.
ABSTRACT Objectives Targeted therapies have markedly improved outcomes in chronic lymphocytic leukaemia (CLL), particularly among patients with TP53 alterations and unmutated IGHV. However, real‐world studies report persistent inequalities in access to optimal care.
Susana Esteves, Inês Coelho, José Carda, Sara Duarte, Inês Carvalhais, Daniela Alves, Rita Coutinho, Maria Gomes da Silva   +7 more
wiley   +1 more source

Comparative Efficacy of Metabolic/Bariatric Surgery Versus GLP‐1 Receptor Agonists: A Network Meta‐Analysis of Randomized Controlled Trials

Obesity, Volume 34, Issue 4, Page 770-781, April 2026.
ABSTRACT Objective This study compared the efficacy of metabolic/bariatric surgery (MBS) and GLP‐1 receptor agonists (GLP‐1 RAs), including dual GLP‐1/GIP analogues, for weight and metabolic outcomes in adults with obesity. Methods A network meta‐analysis of randomized controlled trials compared MBS or GLP‐1 RAs versus lifestyle intervention in adults ...
Lucas Sabatella, Patricia M. Ortega, Víctor Valentí Azcárate, Fernando Rotellar Sastre, Adriana Uriz Pagola, Ahmed Ahmed, Sanjay Purkayastha, Carlota Tuero Ojanguren, Nuria Blanco Asensio, Manuel F. Landecho   +9 more
wiley   +1 more source

Primary hiperoxaluria diagnosed after kidney transplantation: report of 2 cases and literature review

Brazilian Journal of Nephrology
Primary hyperoxaluria (PH) is a very rare genetic disorder; it is characterized by total or partial deficiency of the enzymes related to the metabolism of glyoxylate, with an overproduction of calcium oxalate that is deposited in different organs, mainly
John Fredy Nieto Rios, Monica Zuluaga, Lina Maria Serna Higuita, Adriana Florez, Diana Carolina Bello-Marquez, Arbey Aristizábal, Catalina Ocampo Kohn, Gustavo Adolfo Zuluaga   +7 more
doaj   +1 more source

Young man with acute pain in the hypogastrium: What is the diagnostic?

Clinical Case Reports, 2018
Key Clinical Message Congenital renal anomalies can stay asymptomatic even until adult age and be revealed by occurrence of complications. Clinicians should keep in mind this eventuality, especially in the countries where screening for congenital ...
Youness Jabbour, Souhail Regragui
doaj   +1 more source