A 3D biomimetic OS model was developed by bioprinting an OS‐cell‐derived dECM‐enriched bioink with OS spheroids incorporated. The model showed upregulation of known OS prognostic markers and increased resistance to doxorubicin, compared to 2D cultures and scaffold‐free spheroids, making this a more clinically relevant platform for drug discovery ...
Margarida F. Domingues +6 more
wiley +1 more source
Oxygen Content in SiO <sub><i>x</i></sub> Impacts Chemical Prelithiation Kinetics, Swelling, and Lithium Partitioning. [PDF]
Lin Z, Fang ZZ, Sun P.
europepmc +1 more source
A bioassembly approach is described using photo‐crosslinked gelatin‐based microgels containing calcium peroxide (CaO2) to generate oxygen (O2) and enhance cell survival in hypoxic conditions (1% O2). Bioassembly enables spatial patterning of individual CaO2‐laden and mesenchymal stem cell (MSC)‐laden microgels and allows for decoupling and mitigating ...
Axel E. Norberg +5 more
wiley +1 more source
Bioinspired Vascular Bundle Structured Nanocellulose/PVDF-HFP Composite Membranes for Efficient Ion Transport and Stable All-Solid-State Lithium Batteries. [PDF]
Gao C, Zhou Y, Huang Y, Wang S, Ma X.
europepmc +1 more source
Peptomer Linkers Enable Kinetic Control over Co‐Delivery of Multiple Chemotherapeutics
A key challenge in combinatorial chemotherapeutic drug delivery is independent control over release kinetics, especially with drugs of similar size and structure. Here, peptoid substitutions to proteolytically degradable peptides enabled the design of fast and slow‐releasing drug linkers.
Carolyn M. Watkins +3 more
wiley +1 more source
Lithium dendrite inhibition effect induced by nucleation parameters based on the mechanical-thermo-electrochemical coupling model. [PDF]
Hao WQ, Xie JM, Hou PY, Wang FH.
europepmc +1 more source
Skin‐Interfaced Therapeutic Patches for Wound Fluid Management and Transdermal Drug Delivery
This study presents an integrated skin‐interfaced device combining microfluidics, hydrogel film technology, flexible electronics, and iontophoresis‐based transdermal delivery of PDRN to enhance wound healing. The device effectively manages wound fluid, maintains optimal moisture, and non‐invasively delivers therapeutic drugs.
Dongjun Han +5 more
wiley +1 more source
Customized composition of lithium metal solid-electrolyte interphase by electric field modulation of anion motion direction. [PDF]
Xu S +12 more
europepmc +1 more source
A Synovium‐on‐Chip Platform to Study Multicellular Interactions in Arthritis
The Synovium‐on‐Chip comprises a thin microporous PDMS membrane to support co‐culture of fibroblast‐like synoviocytes (FLS), THP‐1‐derived macrophages, and endothelial cells, enabling real‐time analysis of synovial‐vascular interactions. FLS migration through the pores drives endothelial remodeling, while TNF‐α stimulation induces robust inflammatory ...
Laurens R. Spoelstra +8 more
wiley +1 more source

