Results 21 to 30 of about 21,792 (297)

Perceptions of using lithium in fracture management: a survey of orthopaedic surgeons, fracture patients and the general public

BMC Musculoskeletal Disorders, 2019
Background Lithium, an established psychiatric medication, has recently been shown to enhance new bone formation in preclinical fracture models. Current research is focused on evaluating the efficacy of low-dose, short-term lithium treatment to improve ...
Kathak Vachhani, Cari M. Whyne, Ayal Schaffer, Diane Nam   +3 more
doaj   +1 more source

Effect of antipsychotics on serum lithium levels and white blood cell counts

Neuropsychopharmacology Reports, 2021
Lithium carbonate is used to increase white blood cell counts as a means of counteracting leukopenia caused by the administration of antipsychotic drugs.
Ryo Obara, Takashi Tomita, Hidekazu Goto, Yukinao Kohda, Tadashi Yoshida, Kenzo Kudo   +5 more
doaj   +1 more source

A mixed methods analysis of lithium-related patient safety incidents in primary care

Therapeutic Advances in Drug Safety, 2020
Background: Lithium is a drug with a narrow therapeutic range and has been associated with a number of serious adverse effects. This study aimed to characterise primary care lithium-related patient safety incidents submitted to the National Reporting and
Richard Simon Young, Paul Deslandes, Jennifer Cooper, Huw Williams, Joyce Kenkre, Andrew Carson-Stevens   +5 more
doaj   +1 more source

Parkinson’s Disease: Potential Actions of Lithium by Targeting the WNT/β-Catenin Pathway, Oxidative Stress, Inflammation and Glutamatergic Pathway

Cells, 2021
Parkinson’s disease (PD) is one of the major neurodegenerative diseases (ND) which presents a progressive neurodegeneration characterized by loss of dopamine in the substantia nigra pars compacta.
Alexandre Vallée, Jean-Noël Vallée, Yves Lecarpentier   +2 more
doaj   +1 more source

Lithium-related medication problems on nonpsychiatric inpatient medical units

American Journal of Health-System Pharmacy, 2019
Abstract Purpose Results of a study of medication-related problems (MRPs) associated with lithium use on nonpsychiatric inpatient medical units are reported. Methods In a single-center, retrospective study, the records of all patients
Jennifer N, Alastanos, Teresa G, Potter, Ericka L, Crouse   +2 more
openaire   +2 more sources

Identification and characterization of preventable adverse drug events in family medicine clinics from central Saudi Arabia

Saudi Journal of Medicine and Medical Sciences, 2023
Background: Medication errors can result in adverse drug events (ADEs) and cause considerable patient harm. Limited data are available from Saudi Arabia and the Middle East regarding the prevalence of preventable adverse drug events (pADEs) in primary ...
Ghadah A Assiri, Abdulelah S Bin Shihah, Mohammed K Alkhalifah, Ali S Alshehri, Abdullah H Alkhenizan   +4 more
doaj   +1 more source

Lithium: a potential therapeutic strategy in obsessive–compulsive disorder by targeting the canonical WNT/β pathway

Translational Psychiatry, 2021
Obsessive–compulsive disorder (OCD) is a neuropsychiatric disorder characterized b–y recurrent and distinctive obsessions and/or compulsions. The etiologies remain unclear.
Alexandre Vallée, Jean-Noël Vallée, Yves Lecarpentier   +2 more
doaj   +1 more source

Population Pharmacokinetics and Dosing Regimen of Lithium in Chinese Patients With Bipolar Disorder

Frontiers in Pharmacology, 2022
Background: Lithium is an effective medication approved for the treatment of bipolar disorder (BD). It has a narrow therapeutic index (TI) and requires therapeutic drug monitoring.
Zi-bin Jin, Zhuo Wu, Yi-fan Cui, Yi-fan Cui, Xue-peng Liu, Hong-bo Liang, Jia-yong You, Chen-yu Wang   +7 more
doaj   +1 more source

Transcription-Driven Repurposing of Cardiotonic Steroids for Lithium Treatment of Severe Depression

Cells
Lithium is prescribed as a mood stabilizer for bipolar disorder and severe depression. However, the mechanism of action of lithium is unknown and there are major side effects associated with prolonged medication.
Richard Killick, Claudie Hooper, Cathy Fernandes, Christina Elliott, Dag Aarsland, Svein R. Kjosavik, Ragnhild Østerhus, Gareth Williams   +7 more
doaj   +1 more source

Facial processing in bipolar disorder is mediated by clinical and biological aspects

Brazilian Journal of Psychiatry, 2022
Objective: The process of detecting faces can be considered one of the initial steps in face recognition, which is essential for human interaction. We sought to investigate whether a face perception task reliably detects subtle perceptual disturbances ...
Irina I. Shoshina, Milena E. Oliveira, Gabriella M. Silva, Nathalia S. Negreiros, Fatima M. Felisberti, Thiago P. Fernandes, Natanael A. Santos   +6 more
doaj   +1 more source