Results 31 to 40 of about 44,376 (309)

Medication treatment perceptions, concerns and expectations among depressed individuals with Type I Bipolar Disorder [PDF]

, 2009
BACKGROUND: Subjective experience of illness affects outcomes among populations with bipolar disorder (BD). This cross-sectional study combined qualitative and quantitative approaches to evaluate perceived treatment effects, concerns and expectations ...
Cassidy, Kristin A, Jenkins, Janis H, Muzina, David J, Sajatovic, Martha   +3 more
core   +1 more source

A functional variant in the serotonin receptor 7 gene (HTR7), rs7905446, is associated with good response to SSRIs in bipolar and unipolar depression. [PDF]

, 2020
Predicting antidepressant response has been a clinical challenge for mood disorder. Although several genome-wide association studies have suggested a number of genetic variants to be associated with antidepressant response, the sample sizes are small and
Aitchison, Katherine J, Binder, Elisabeth B, Carrillo-Roa, Tania, Cattaneo, Annamaria, DeModena, Anna, Henigsberg, Neven, Kelsoe, John R, Leckband, Susan G, Liu, Jia Jia, McCarthy, Michael, Mors, Ole, Ren, Hongyan, Rietschel, Marcella, Shekhtman, Tatyana, Wei, Ya Bin   +14 more
core   +2 more sources

Can We Really Prevent Suicide? [PDF]

, 2012
Every year, suicide is among the top 20 leading causes of death globally for all ages. Unfortunately, suicide is difficult to prevent, in large part because the prevalence of risk factors is high among the general population. In this review, clinical and
A Fagiolini, A Roy, A Roy, AC Leon, AD Lopez, AF Jorm, AL Beautrais, AN Sabo, AP Chioqueta, B Schneider, B Schneider, B Spivac, B Stanely, B Stanley, B Yerevanian, BA Palmer, BN Gaynes, C Bushe, C Haw, CM Feltz-Cornelis van der, CW Tsai, D Fergusson, D Gunnell, D Shaffer, D Wasserman, DA Brent, DA Brent, DA Brent, EC Harris, F Cassidy, F Guzzetta, F Keller, FK Goodwin, FS Bridges, G Dieserud, G Isacsson, G Isacsson, G Sonneck, Gil Zalsman, GK Brown, GL Carter, GL Sidley, H Dumesnil, H Galfalvy, H Valtonen, HG Morgan, HJ Moller, HJ Moller, HJ Moller, HY Meltzer, J Fawcet, J Johnson, J Lonnqvist, JA Egeland, JB Luoma, JD Maser, JJ Lin, JJ Mann, JJ Mann, JM Boden, JMG Williams, K Hawton, K Hor, K Posner, K Szanto, KL Knox, KM Malone, L Tondo, LM Hayes, Lucas Giner, M Bauer, M Bauer, M Leitner, M Miller, M Olfson, M Panagioti, M Pompili, M Sarchiapone, M Shelef, MA Oquendo, MA Oquendo, MA Oquendo, MA Oquendo, Maria A. Oquendo, Maya Schwartz-Lifshitz, MD Rudd, MM Linehan, MP Pignone, N Tarrier, ND Kapusta, NM Melhem, O Bennewith, PA Wyman, PG Placidi, PH Soloff, PH Soloff, RD Gibbons, RJ Baldessarini, S Kelly, SH Kennedy, SP Pirkola, U Hegerl, U Hegerl, U Hegerl, UA Andersen, W Coryell, WA Watson, WD Hall, Z Rihmer, Z Rihmer, Z Rihmer, Z Rihmer   +111 more
core   +1 more source

Cognitive function and lifetime features of depression and bipolar disorder in a large population sample: Cross-sectional study of 143,828 UK Biobank participants [PDF]

, 1996
Background: This study investigated differences in cognitive performance between middle-aged adults with and without a lifetime history of mood disorder features, adjusting for a range of potential confounders.
Cullen, B., Deary, I..J., Evans, J.J., Gallacher, J., Mackay, D.F., Martin, D., McIntosh, A., Nicholl, B.I., Pell, J.P., Smith, D.J., Ul-Haq, Z.   +10 more
core   +2 more sources

Facial processing in bipolar disorder is mediated by clinical and biological aspects

Brazilian Journal of Psychiatry, 2022
Objective: The process of detecting faces can be considered one of the initial steps in face recognition, which is essential for human interaction. We sought to investigate whether a face perception task reliably detects subtle perceptual disturbances ...
Irina I. Shoshina, Milena E. Oliveira, Gabriella M. Silva, Nathalia S. Negreiros, Fatima M. Felisberti, Thiago P. Fernandes, Natanael A. Santos   +6 more
doaj   +1 more source

“Ghost tablet” husks excreted in feces in large bupropion XL overdose [PDF]

, 2018
Background: Extended-release medications are widely prescribed across the spectrum of medical specialties; however, there is heterogeneity in how they are formulated.
Nanagas, Kristine, Overberg, Adam, Purpura, Andrea   +2 more
core   +1 more source

Transcription-Driven Repurposing of Cardiotonic Steroids for Lithium Treatment of Severe Depression

Cells
Lithium is prescribed as a mood stabilizer for bipolar disorder and severe depression. However, the mechanism of action of lithium is unknown and there are major side effects associated with prolonged medication.
Richard Killick, Claudie Hooper, Cathy Fernandes, Christina Elliott, Dag Aarsland, Svein R. Kjosavik, Ragnhild Østerhus, Gareth Williams   +7 more
doaj   +1 more source

Challenging the Safety Threshold: Neurotoxicity in Bipolar Disorder Treatment with Lithium at Therapeutic Serum Levels

Psychiatry and Clinical Psychopharmacology
Bipolar disorder is a complex mental disorder that often requires long-term medication management. Lithium carbonate is widely used to prevent and treat the recurrence of bipolar disorder.
Jinbo Chen, Jun Zhu, Hehua Bao, Lijuan Tang, Benhan Li, Zixuan Chen, Yanli Zhang, Qiang Hu   +7 more
doaj   +1 more source

High lithium concentration at delivery is a potential risk factor for adverse outcomes in breastfed infants: a retrospective cohort study

International Journal of Bipolar Disorders, 2023
Background Neonatal effects of late intrauterine and early postpartum exposure to lithium through mother’s own milk are scarcely studied. It is unclear whether described symptoms in breastfed neonates are caused by placental lithium transfer or postnatal
Essi Whaites Heinonen, Katarina Tötterman, Karin Bäck, Ihsan Sarman, Lisa Forsberg, Jenny Svedenkrans   +5 more
doaj   +1 more source

Persistent lithium-induced neurotoxicity: direct effect of lithium and/or hypernatremia? [PDF]

, 2009
Lithium has been used in the treatment of bipolar affective disorder (BAD) for more than 50 years. Features of lithium toxicity include drowsiness, slurred speech, ataxia, psychomotor slowing, polyneuropathy, impaired memory, seizures, coma and death ...
Bourgeois, James A., Popescu, Ioana-Mihaela   +1 more
core   +2 more sources