Results 21 to 30 of about 22,437 (256)

Effect of antipsychotics on serum lithium levels and white blood cell counts

Neuropsychopharmacology Reports, 2021
Lithium carbonate is used to increase white blood cell counts as a means of counteracting leukopenia caused by the administration of antipsychotic drugs.
Ryo Obara, Takashi Tomita, Hidekazu Goto, Yukinao Kohda, Tadashi Yoshida, Kenzo Kudo   +5 more
doaj   +1 more source

Parkinson’s Disease: Potential Actions of Lithium by Targeting the WNT/β-Catenin Pathway, Oxidative Stress, Inflammation and Glutamatergic Pathway

Cells, 2021
Parkinson’s disease (PD) is one of the major neurodegenerative diseases (ND) which presents a progressive neurodegeneration characterized by loss of dopamine in the substantia nigra pars compacta.
Alexandre Vallée, Jean-Noël Vallée, Yves Lecarpentier   +2 more
doaj   +1 more source

Identification and characterization of preventable adverse drug events in family medicine clinics from central Saudi Arabia

Saudi Journal of Medicine and Medical Sciences, 2023
Background: Medication errors can result in adverse drug events (ADEs) and cause considerable patient harm. Limited data are available from Saudi Arabia and the Middle East regarding the prevalence of preventable adverse drug events (pADEs) in primary ...
Ghadah A Assiri, Abdulelah S Bin Shihah, Mohammed K Alkhalifah, Ali S Alshehri, Abdullah H Alkhenizan   +4 more
doaj   +1 more source

Lithium: a potential therapeutic strategy in obsessive–compulsive disorder by targeting the canonical WNT/β pathway

Translational Psychiatry, 2021
Obsessive–compulsive disorder (OCD) is a neuropsychiatric disorder characterized b–y recurrent and distinctive obsessions and/or compulsions. The etiologies remain unclear.
Alexandre Vallée, Jean-Noël Vallée, Yves Lecarpentier   +2 more
doaj   +1 more source

Population Pharmacokinetics and Dosing Regimen of Lithium in Chinese Patients With Bipolar Disorder

Frontiers in Pharmacology, 2022
Background: Lithium is an effective medication approved for the treatment of bipolar disorder (BD). It has a narrow therapeutic index (TI) and requires therapeutic drug monitoring.
Zi-bin Jin, Zhuo Wu, Yi-fan Cui, Yi-fan Cui, Xue-peng Liu, Hong-bo Liang, Jia-yong You, Chen-yu Wang   +7 more
doaj   +1 more source

Effects of Erratic Lithium Usage: Sinus Bradycardia and Hyperpigmentation

Medical Journal of Dr. D.Y. Patil Vidyapeeth
Lithium toxicity is a serious, potentially life-threatening condition, often resulting from inconsistent medication adherence, dehydration, or renal impairment.
Ajas Asharaf, Safna Hameed, Pravya Udhayan, R. Ameer, Diya Elizabeth Manoj, K. Ebenz Chalson, Sai Keerthana Puthiyedath Cheruvatta   +6 more
doaj   +1 more source

Transcription-Driven Repurposing of Cardiotonic Steroids for Lithium Treatment of Severe Depression

Cells
Lithium is prescribed as a mood stabilizer for bipolar disorder and severe depression. However, the mechanism of action of lithium is unknown and there are major side effects associated with prolonged medication.
Richard Killick, Claudie Hooper, Cathy Fernandes, Christina Elliott, Dag Aarsland, Svein R. Kjosavik, Ragnhild Østerhus, Gareth Williams   +7 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Challenging the Safety Threshold: Neurotoxicity in Bipolar Disorder Treatment with Lithium at Therapeutic Serum Levels

Psychiatry and Clinical Psychopharmacology
Bipolar disorder is a complex mental disorder that often requires long-term medication management. Lithium carbonate is widely used to prevent and treat the recurrence of bipolar disorder.
Jinbo Chen, Jun Zhu, Hehua Bao, Lijuan Tang, Benhan Li, Zixuan Chen, Yanli Zhang, Qiang Hu   +7 more
doaj   +1 more source

Facial processing in bipolar disorder is mediated by clinical and biological aspects

Brazilian Journal of Psychiatry, 2022
Objective: The process of detecting faces can be considered one of the initial steps in face recognition, which is essential for human interaction. We sought to investigate whether a face perception task reliably detects subtle perceptual disturbances ...
Irina I. Shoshina, Milena E. Oliveira, Gabriella M. Silva, Nathalia S. Negreiros, Fatima M. Felisberti, Thiago P. Fernandes, Natanael A. Santos   +6 more
doaj   +1 more source