Results 31 to 40 of about 1,183,219 (341)

Association of Attention-Deficit/Hyperactivity Disorder and Depression Polygenic Scores with Lithium Response: A Consortium for Lithium Genetics Study

Complex Psychiatry, 2021
Response to lithium varies widely between individuals with bipolar disorder (BD). Polygenic risk scores (PRSs) can uncover pharmacogenomics effects and may help predict drug response.
B. Coombes, V. Millischer, A. Batzler, Beth Larrabee, L. Hou, S. Papiol, U. Heilbronner, M. Adli, K. Akiyama, N. Akula, Azmeraw T. Amare, R. Ardau, B. Arias, J. Aubry, L. Backlund, M. Bauer, B. Baune, F. Bellivier, A. Benabarre, S. Bengesser, A. Bhattacharjee, P. Cervantes, Hsi-Chung Chen, C. Chillotti, S. Cichon, S. Clark, F. Colom, C. Cruceanu, P. Czerski, N. Dalkner, F. Degenhardt, M. Del Zompo, J. DePaulo, B. Étain, P. Falkai, E. Ferensztajn-Rochowiak, A. Forstner, L. Frisén, S. Gard, J. Garnham, F. Goes, M. Grigoroiu-Serbanescu, P. Grof, Ryota Hashimoto, J. Hauser, S. Herms, P. Hoffmann, S. Jamain, E. Jiménez, J. Kahn, L. Kassem, Tadafumi Kato, J. Kelsoe, S. Kittel-Schneider, B. König, Po-Hsiu Kuo, I. Kusumi, G. Laje, M. Landén, C. Lavebratt, M. Leboyer, S. Leckband, M. Maj, M. Manchia, Lina Martinsson, M. McCarthy, S. McElroy, P. Mitchell, M. Mitjans, Francis M. Mondimore, P. Monteleone, C. Nievergelt, M. Nöthen, Tomáš Dvořáčková Blanka Novák, C. O’Donovan, U. Osby, N. Ozaki, A. Pfennig, C. Pisanu, J. Potash, A. Reif, E. Reininghaus, M. Rietschel, G. Rouleau, J. Rybakowski, M. Schalling, P. Schofield, K. Schubert, Barbara W. Schweizer, G. Severino, T. Shekhtman, P. Shilling, Katzutaka Shimoda, C. Simhandl, C. Slaney, A. Squassina, T. Stamm, P. Stopková, A. Tortorella, G. Turecki, E. Vieta, S. Witt, P. Zandi, J. Fullerton, M. Alda, M. Frye, T. Schulze, F. McMahon, J. Biernacka   +108 more
semanticscholar   +1 more source

Optimization of dd110 neutron generator output for boron neutron capture therapy [PDF]

Quantum Beam Sci. 2025, 9(2), 12, 2023
Boron neutron capture therapy is about a century old, but still current and active. In this treatment, a high absorption cross-section of boron is used for thermal neutrons and the excited state is decomposed into alpha and lithium ions. These daughter particles have a high LET value and transfer their energy to the surrounding cells. In this work, the
arxiv   +1 more source

Perceptions of using lithium in fracture management: a survey of orthopaedic surgeons, fracture patients and the general public

BMC Musculoskeletal Disorders, 2019
Background Lithium, an established psychiatric medication, has recently been shown to enhance new bone formation in preclinical fracture models. Current research is focused on evaluating the efficacy of low-dose, short-term lithium treatment to improve ...
Kathak Vachhani, Cari M. Whyne, Ayal Schaffer, Diane Nam   +3 more
doaj   +1 more source

A mixed methods analysis of lithium-related patient safety incidents in primary care

Therapeutic Advances in Drug Safety, 2020
Background: Lithium is a drug with a narrow therapeutic range and has been associated with a number of serious adverse effects. This study aimed to characterise primary care lithium-related patient safety incidents submitted to the National Reporting and
Richard Simon Young, Paul Deslandes, Jennifer Cooper, Huw Williams, Joyce Kenkre, Andrew Carson-Stevens   +5 more
doaj   +1 more source

Biological effects of lithium – fundamental and medical aspects [PDF]

The Ukrainian Biochemical Journal, 2017
In this review, the authors present data on the biological effects of lithium in human and animal body and the subsequent manifestations of these effects. Since the lithium ion radius is close to that of magnesium, lithium ion can compete with magnesium as cofactor of certain magnesium-dependent enzymes.
A. S. Mikosha, O. I. Kovzun, M. D. Tronko   +2 more
openaire   +3 more sources

Antidepressant effect of repetitive transcranial magnetic stimulation is not impaired by intake of lithium or antiepileptic drugs

European Archives of Psychiatry and Clinical Neuroscience, 2021
The effect of concomitant medication on repetitive transcranial magnetic stimulation (rTMS) outcomes in depression remains understudied. Recent analyses show attenuation of rTMS effects by antipsychotic medication and benzodiazepines, but data on the ...
T. Hebel, M. Abdelnaim, M. Deppe, P. Kreuzer, A. Mohonko, T. Poeppl, R. Rupprecht, B. Langguth, M. Schecklmann   +8 more
semanticscholar   +1 more source

Solvation and Transport of Lithium Ions in Deep Eutectic Solvents [PDF]

J. Chem. Phys. 153 (2020) 104505, 2020
Lithium based deep eutectic solvents (DESs) are excellent candidates for eco-friendly electrolytes in lithium ion batteries. While some of these DES have shown promising results, a clear mechanism of lithium ion transport in DESs is not yet established.
arxiv   +1 more source

A survey of Saskatchewan family physicians, psychiatrists and pharmacists assessing barriers in lithium use

Journal of Affective Disorders Reports, 2021
Background: Lithium is a popular mood stabilizer. Anecdotally, it is an underutilized medication in primary care. We conducted a survey of family physicians (FPs), pharmacists and psychiatrists in Saskatchewan to examine attitudes towards and knowledge ...
Adebiyi O, Peters E, Marcoux G, Alaverdashvili M, Halpape K, Lodhi RJ   +5 more
doaj  

Population Pharmacokinetics and Dosing Regimen of Lithium in Chinese Patients With Bipolar Disorder

Frontiers in Pharmacology, 2022
Background: Lithium is an effective medication approved for the treatment of bipolar disorder (BD). It has a narrow therapeutic index (TI) and requires therapeutic drug monitoring.
Zi-bin Jin, Zhuo Wu, Yi-fan Cui, Yi-fan Cui, Xue-peng Liu, Hong-bo Liang, Jia-yong You, Chen-yu Wang   +7 more
doaj   +1 more source

Controlling $\text{Li}^+$ transport in ionic liquid electrolytes through salt content and anion asymmetry: A mechanistic understanding gained from molecular dynamics simulations [PDF]

, 2021
In this work, we report the results from molecular dynamics simulations of lithium salt-ionic liquid electrolytes (ILEs) based either on the symmetric bis[(trifluoromethyl)sulfonyl]imide ($\text{TFSI}^-$) anion or its asymmetric analog 2,2,2-(trifluoromethyl)sulfonyl-N-cyanoamide ($\text{TFSAM}^-$).
arxiv   +1 more source