Results 71 to 80 of about 289,721 (306)

Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis

Hepatology, EarlyView., 2022
Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis. Abstract Background and Aims Nucleotide‐binding oligomerization domain‐like receptor‐family pyrin domain‐containing 3 (NLRP3) inflammasome activation has been shown to result in liver fibrosis.
Jana Knorr, Benedikt Kaufmann, Maria Eugenia Inzaugarat, Theresa Maria Holtmann, Lukas Geisler, Jana Hundertmark, Marlene Sophia Kohlhepp, Laela M. Boosheri, Daisy R. Chilin‐Fuentes, Amanda Birmingham, Kathleen M. Fisch, Joel D. Schilling, Sven H. Loosen, Christian Trautwein, Christoph Roderburg, Münevver Demir, Frank Tacke, Hal M. Hoffman, Ariel E. Feldstein, Alexander Wree   +19 more
wiley   +1 more source

A review of factors influencing litter size in Irish sows

Irish Veterinary Journal, 2007
Many factors influence litter size. These include genetics, gilt management, lactation length, parity distribution, disease, stress and boar fertility. In the past 20 years, litter size in Irish sows has increased by only one pig.
Lawlor Peadar G, Lynch P Brendan
doaj   +1 more source

LITTERBASE - Online Portal for Marine Litter & Microplastics and their Implications for Marine Life [PDF]

, 2018
Contamination of the oceans with anthropogenic litter is a global environmental problem which currently receives increasing attention by scientists, policy makers, public authorities, media and the general public.
Bergmann, Melanie, Gutow, Lars, Peter, Corina, Tekman, Mine Banu   +3 more
core  

Genetic analysis of litter size in mice

Journal of Veterinary Medical Science, 2015
We performed quantitative trait locus (QTL) mapping analysis for litter size (total number of pups born and/or number of pups born alive) in 255 backcross mice derived from C57BL/6J and RR/Sgn inbred mice. We identified one significant QTL on chromosome 7 and 4 suggestive QTLs on chromosomes 3, 5, 10 and 13.
openaire   +3 more sources

SIRT5–RAC2 Axis Drives Monocyte‐to‐Macrophage Differentiation to Promote Inflammatory Injury in Premature Ovarian Insufficiency

Advanced Science, EarlyView.
SIRT5 desuccinylates and stabilizes RAC2, activating CSF1R‐dependent signaling to drive monocyte differentiation into M0 macrophages and their polarization toward pro‐inflammatory M1 phenotypes in CTX‐induced premature ovarian insufficiency. Inhibiting the SIRT5‐RAC2 axis attenuates inflammation, reduces granulosa cell apoptosis, and preserves ...
Wenjing TanTai, Yaqi Li, Shengnan Liu, Minjuan Wu, Zhixiao Liu, Junfeng Jiang, Jingjing Chen, Xiaoding Xu, Li Li, Chaoqun Li, Fang Zhao, Ye Liu, Haitao Ni, Tengfei Zhang, Mingjuan Xu, Chaofeng Han   +15 more
wiley   +1 more source

Litter Size and Lamb Survivability of Batur Sheep in Upland Areas of Banjarnegara Regency, Indonesia [PDF]

, 2011
. The objective of the current study was to find out the litter size and lamb survivability of Batur sheep, and also to identify the effects of ewe parities on litter size and lamb survivability; and the effects of birth type on lamb survivability of ...
Santosa, S. (SA), Sodiq, A. (A), Yuwono, P. (P)   +2 more
core   +2 more sources

Epidemics on random intersection graphs [PDF]

, 2014
In this paper we consider a model for the spread of a stochastic SIR (Susceptible $\to$ Infectious $\to$ Recovered) epidemic on a network of individuals described by a random intersection graph.
Ball, Frank G., Sirl, David J., Trapman, Pieter   +2 more
core   +4 more sources

miR‐135a‐5p Is a Promising Target to Prevent the Glomerulosclerosis Associated with Podocyte Developmental Toxicity in Offspring Induced by Prenatal Dexamethasone Exposure

Advanced Science, EarlyView.
Prenatal dexamethasone exposure (PDE) programs persistent podocyte developmental injury and adult glomerulosclerosis. Mechanistically, glucocorticoid receptor (GR) binds the miR‐135a‐5p promoter and recruits the histone acetyltransferase p300, increasing promoter histone acetylation and sustaining miR‐135a‐5p expression. Elevated miR‐135a‐5p suppresses
Xiaoqi Zhao, Haiyun Chen, Yanan Zhu, Zhiping Xia, Hangyuan He, Yutang Liu, Tianshu Yang, Hui Wang, Ying Ao   +8 more
wiley   +1 more source

Offspring number, size, and survival: State‐dependent optimization of litter size in a long‐lived capital breeder

Ecosphere
Seventy‐five years ago, Lack proposed that there should be an optimal clutch size shared by all individuals in a population and favored by natural selection, which maximizes the number of recruited offspring.
Marwan Naciri, Jon Aars, Magnus Andersen, Marie‐Anne Blanchet, Andrew E. Derocher, Marlène Gamelon, Øystein Wiig, Sarah Cubaynes   +7 more
doaj   +1 more source

Gestational and lactational exposure of rats to xenoestrogens results in reduced testicular size and sperm production [PDF]

, 1995
EHP is a publication of the U.S. government. Publication of EHP lies in the public domain and is therefore without copyright. Research articles from EHP may be used freely; however, articles from the News section of EHP may contain photographs or ...
Albro P, Berndtson WE, J P Sumpter, J S Fisher, M M Millar, McLachlan JA, R M Sharpe, S Jobling, Sharpe RM   +8 more
core   +2 more sources