Results 31 to 40 of about 8,186,764 (283)

The Economic Impact of the Little Ice Age [PDF]

SSRN Electronic Journal, 2010
We investigate by how much the Little Ice Age reduced the harvests on which pre-industrial Europeans relied for survival. We find that weather strongly affected crop yields, but can find little evidence that western Europe experienced long swings or structural breaks in climate.
Kelly, Morgan, Ó Gráda, Cormac
openaire   +3 more sources

Genome‐wide evolutionary response of European oaks during the Anthropocene

Evolution Letters, 2022
The pace of tree microevolution during Anthropocene warming is largely unknown. We used a retrospective approach to monitor genomic changes in oak trees since the Little Ice Age (LIA).
Dounia Saleh, Jun Chen, Jean‐Charles Leplé, Thibault Leroy, Laura Truffaut, Benjamin Dencausse, Céline Lalanne, Karine Labadie, Isabelle Lesur, Didier Bert, Frédéric Lagane, François Morneau, Jean‐Marc Aury, Christophe Plomion, Martin Lascoux, Antoine Kremer   +15 more
doaj   +1 more source

The Little Ice Age in Scientific Perspective: Cold Spells and Caveats [PDF]

, 2014
Contrary to the position taken by Kelly and Ó Gráda, a rich body of regional- to large-scale temperature reconstructions that span from the last millennium to almost the entire Holocene confirms the existence of several temperature depressions that ...
Büntgen, Ulf, Hellmann, Lena, Büntgen, Ulf (author), Hellmann, Lena (author)   +3 more
core   +2 more sources

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Reconstructing ice-sheet accumulation rates at ridge B, East Antarctica [PDF]

, 2004
Understanding how ice sheets responded to past climate change is fundamental to forecasting how they will respond in the future. Numerical models calculating the evolution of ice sheets depend upon accumulation data, which are principally available from ...
Payne, Antony J, Leysinger Vieli, G.J.-M.C., Payne, A. J., Siegert, MJ, Payne, AJ, Leysinger Vieli, GJMC, Leysinger Vieli, Gwendolyn, Siegert, Martin J, Siegert, M. J., Martin J. Siegert, Antony J. Payne, Gwendolyn J.-M. C. Leysinger Vieli   +11 more
core   +1 more source

Accelerating Glacier Area Loss Across the Andes Since the Little Ice Age

Geophysical Research Letters
Andean glaciers are losing mass rapidly but a centennial‐scale context to those rates is lacking. Here we show the extent of >5,500 glaciers during the Little Ice Age chronozone (LIA; c. 1,400 to c.
Jonathan L. Carrivick, Morwenna Davies, Ryan Wilson, Bethan J. Davies, Tom Gribbin, Owen King, Antoine Rabatel, Juan‐Luis García, Jeremy C. Ely   +8 more
doaj   +1 more source

Touching the cold in the Little Ice Age

Lychnos
Climate change urges us to reconsider the very cold. Its natural manifestations – ice and snow – are today shrinking elements, and the gravity of melting glaciers and thawing polar regions is indeed deeply worrying for the planet as a whole.
Cecilia Rosengren
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Frost fairs, sunspots and the Little Ice Age [PDF]

, 2017
Mike Lockwood, Mat Owens, Ed Hawkins, Gareth S. Jones and Ilya Usoskin examine the links between the solar Maunder minimum, the Little Ice Age and the freezing of the River ...
Mat Owens, Hawkins, Ed, Hawkins , Ed, Lockwood, Mike, Ed Hawkins, Gareth S Jones, Owens , Mat, Ilya Usoskin, Usoskin, Ilya, Jones, Gareth S., Usoskin , Ilya, Owens, Mat, Mike Lockwood, Jones, Gareth   +13 more
core   +1 more source