Results 61 to 70 of about 124,423 (252)
Little Ice Age in Romania in the Vision of a Syrian Traveler
Present Environment and Sustainable Development, 2014 Archdeacon Paul of Aleppo of Damascus accompanied the Patriarch Macarios of Antioch, in Moldavia, Wallachia, Dobrogea for nearly seven years (1652-1659), just in time considered one of the coldest during the Little Ice Age, Maunder Minimum namely (1645 ...
Teodoreanu Elena
doaj +1 more source
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
Mapping glaciers in Jotunheimen, South-Norway, during the "Little Ice Age" maximum [PDF]
The Cryosphere, 2009 The maximum glacier extent during the "Little Ice Age" (mid 18th century AD) in Jotunheimen, southern Norway, was mapped using remote sensing techniques.
S. Baumann, S. Winkler, L. M. Andreassen
doaj
The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp +4 more
wiley +1 more source
Dynamics of mountain glaciation in the South-Eastern Siberia over the past 160 years
Лëд и снег, 2015 Changes in areas of glaciers in three South-East Siberian mountainous regions (East Sayan, Baikalsky and Kodar ridges) had been analyzed for the period since end of Little Ice Age (LIA) to the present time (about 160 years).
E. Y. Osipov, O. P. Osipova
doaj +1 more source
Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird +9 more
wiley +1 more source
Fluctuating selection and rapid evolution of oaks during recent climatic transitions
Plants, People, PlanetSocietal Impact Statement The rapidity of evolutionary changes in trees and whether this pace is sufficient to cope with ongoing climatic change are hotly debated issues in ecology today.
Thomas Caignard +6 more
doaj +1 more source
Destabilisation of the Subpolar North Atlantic prior to the Little Ice Age. [PDF]
Nat Commun, 2022 Arellano-Nava B +6 more
europepmc +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian +6 more
wiley +1 more source
Defining the Little Ice Age [PDF]
, 2010 Abstract. The "Little Ice Age" (LIA) is possibly the best-documented climatic anomaly of the past. A wide range of datasets portrays a harsh climate that worsened living conditions, primarily in terms of cooler temperatures, for people across Europe sometime during the last millennium.
Paasche, Ø., Bakke, J.
openaire +2 more sources