Results 71 to 80 of about 122,239 (253)

Dynamics of mountain glaciation in the South-Eastern Siberia over the past 160 years

Лëд и снег, 2015
Changes in areas of glaciers in three South-East Siberian mountainous regions (East Sayan, Baikalsky and Kodar ridges) had been analyzed for the period since end of Little Ice Age (LIA) to the present time (about 160 years).
E. Y. Osipov, O. P. Osipova
doaj   +1 more source

Destabilisation of the Subpolar North Atlantic prior to the Little Ice Age. [PDF]

Nat Commun, 2022
Arellano-Nava B, Halloran PR, Boulton CA, Scourse J, Butler PG, Reynolds DJ, Lenton TM.   +6 more
europepmc   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

SOLAR-FORCED 2600 BP AND LITTLE ICE AGE HIGHSTANDS OF THE CASPIAN SEA

Юг России: экология, развитие, 2015
The researches combining a social, economic and ecological content, find out a generality of appendix area and global purpose. This purpose image is hidden behind the term sustainable development".
S. B. Kroonenberg, G. M. Abdurakhmanov, E. N. Badyukova, K. van der Borg, A. Kalashnikov, N. S. Kasimov, G. I. Rychagov, A. A. Svitoch, H. B. Vonhof, F. P. Wesselingh   +9 more
doaj   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Author Correction: Split westerlies over Europe in the early Little Ice Age. [PDF]

Nat Commun, 2022
Hu HM, Shen CC, Chiang JCH, Trouet V, Michel V, Tsai HC, Valensi P, Spötl C, Starnini E, Zunino M, Chien WY, Sung WH, Chien YT, Chang P, Korty R.   +14 more
europepmc   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the feasibility of classical (CH50) and alternative (AH50) complement pathway activity as potential biomarkers for treatment guidance and monitoring during therapy with ravulizumab in patients with generalized myasthenia gravis (gMG) and compare these to therapeutic drug monitoring under eculizumab.
Lea Gerischer, Frauke Stascheit, Maximilian Mönch, Paolo Doksani, Carla Dusemund, Meret Herdick, Philipp Mergenthaler, Maike Stein, Amani Suboh, Jutta Schröder‐Braunstein, Guido Wabnitz, Jan D. Lünemann, Sophie Lehnerer, Sarah Hoffmann, Andreas Meisel   +14 more
wiley   +1 more source

New Estimation of the Post Little Ice Age Relative Sea Level Rise

Geosciences, 2019
The study area is located in NW Sardinia Island (Italy), Mediterranean Sea. Sardinia is considered stable since the late Pliocene with a negligible subsidence of about 0.01 mm/y.
Vincenzo Pascucci, Gabriela Frulio, Stefano Andreucci   +2 more
doaj   +1 more source

Little Ice Age abruptly triggered by intrusion of Atlantic waters into the Nordic Seas. [PDF]

Sci Adv, 2021
Lapointe F, Bradley RS.
europepmc   +1 more source