Results 41 to 50 of about 9,093,191 (259)

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang, Dongxu Zhang, Dongyuan Liu, Da Lin, Hao Wang   +4 more
wiley   +1 more source

Reducing Bias in Beta Regression Models Using Jackknifed Liu-Type Estimators: Applications to Chemical Data

Journal of Mathematics
In the field of chemical data modeling, it is common to encounter response variables that are constrained to the interval (0, 1). In such cases, the beta regression model is often a more suitable choice for modeling.
Solmaz Seifollahi, Hossein Bevrani, Olayan Albalawi   +2 more
doaj   +1 more source

Enhancing Poisson-inverse Gaussian ridge-type estimation for overdispersed and multicollinear data: Properties, estimation techniques, and application [PDF]

AIP Advances
The Poisson inverse Gaussian regression model (PIGRM) is widely used for modeling overdispersion in count data, outperforming baseline Poisson and negative binomial regression models, particularly when dealing with longer tails and higher kurtosis data ...
Fatimah M. Alghamdi, Ali T. Hammad, Gizachew Tirite Gellow, Gamal A. Abd-Elmougod, Ahmed M. Gemeay, Eslam Hussam   +5 more
doaj   +1 more source

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin, Tianyuan Yang, Minglei Liu, Haiyang Luo, Jing Yuan, Ke Zhang, Xinsheng Han, Jing Yang, Yuming Xu   +8 more
wiley   +1 more source

A new stochastic restricted Liu-type estimator in linear regression model

, 2019
In this paper, we proposed an alternative stochastic restricted Liu-type estimator for the vector of parameters in a linear regression model. The new estimator is a combination of ordinary mixed estimator and Liu-Type estimator , which was proposed by ...
YILDIZ, NİLGÜN
core   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source

A Comparative Study of Some Two –Parameter Ridge-Type and Liu-Type Estimators to Combat Multicollinearity Problem in Regression Models: Simulation and Application [PDF]

المجلة العلمية للاقتصاد والتجارة
In multiple linear regression analysis, the ordinary least squares (OLS) method has been the most popular technique for estimating parameters of linear regression model due to its optimal properties.
Wael Saad Hsanein El-doakly
doaj   +1 more source

Difference based ridge and Liu type estimators in semiparametric regression models [PDF]

Journal of Multivariate Analysis, 2011
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Esra Akdeniz Duran, Wolfgang K. Härdle, Maria Osipenko   +2 more
openaire   +3 more sources

Nationwide Survey of Association Between Fever and Epileptic Seizure in CDKL5 Deficiency Disorder Revealed Therapeutic Implications

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective CDKL5 deficiency disorder (CDD) is a rare, severe developmental and epileptic encephalopathy. There is a pressing need to develop effective and sustainable therapeutic strategies. We aimed to investigate the causal association between febrile episodes and epileptic seizures for therapeutic implications in CDD patients.
Siyi Wang, Jialin Du, Jinghui Liu, Dongmei Hu, Hongxin Wang, Xiaoxiao Man, Lehong Gao, Shimin Hu, Xianghong Meng, Hongyang Zhao, Minjing Hu, Yingxue Yang, Zhiqi Xiong, Liankun Ren   +13 more
wiley   +1 more source

A Novel Shrinkage Class for the Negative Binomial Regression Model: Theory, Simulation, and Healthcare Application in Saudi Arabia

Mathematical and Computational Applications
Count data are widely encountered in many scientific fields, particularly in healthcare and epidemiology. One of the most commonly used approaches for analyzing such data is the negative binomial regression model (NBRM), due to its simplicity and ...
Eslam Hussam, A. M. A. Gemeay, M. M. Abd El-Raouf, Ramy Aldallal, M. S. Mohamed, A. T. A. Hammad   +5 more
doaj   +1 more source