Rational Design of Live-Attenuated Vaccines against Herpes Simplex Viruses [PDF]
Diseases caused by human herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) affect millions of people worldwide and range from fatal encephalitis in neonates and herpes keratitis to orofacial and genital herpes, among other manifestations.
Brent A. Stanfield +3 more
doaj +2 more sources
Engineering live attenuated vaccines: Old dogs learning new tricks [PDF]
Autoimmune diseases such as rheumatoid arthritis and type 1 diabetes are increasingly common global problems. Concerns about increases in the prevalence of such diseases and the limited efficacy of conventional treatment regimens necessitates new ...
Julia Plocica +7 more
doaj +2 more sources
Live-Attenuated Vaccines in Pediatric Solid Organ Transplant [PDF]
Measles, mumps, rubella (MMR), and varicella incidence rates have increased due to the delayed vaccination schedules of children secondary to the COVID-19 pandemic. Decreased herd immunity creates a risk for immunocompetent children and immunocompromised
Christopher Hartley +3 more
doaj +2 more sources
Viral Live‐Attenuated Vaccines (LAVs): Past and Future Directions [PDF]
Viral infections continue to pose a significant threat to the health of both humans and animals. Currently, live attenuated vaccines (LAVs) remain the most efficacious and widely utilized tool for combating viral infections. Conventional LAVs involve the
Yan‐Dong Tang +3 more
doaj +2 more sources
Live Attenuated Vaccines against Tuberculosis: Targeting the Disruption of Genes Encoding the Secretory Proteins of Mycobacteria [PDF]
Tuberculosis (TB), a chronic infectious disease affecting humans, causes over 1.3 million deaths per year throughout the world. The current preventive vaccine BCG provides protection against childhood TB, but it fails to protect against pulmonary TB ...
Raja Veerapandian +3 more
doaj +2 more sources
PROTAC vaccine: A new way to live attenuated vaccines [PDF]
Zhen Li +6 more
doaj +2 more sources
Preclinical and clinical experience with dupilumab on the correlates of live attenuated vaccines. [PDF]
Wechsler ME +15 more
europepmc +2 more sources
Quality control procedure for Coccidial vaccines versus different routes of immunization [PDF]
Background and Aim: Coccidiosis is an enteric infection caused by a protozoon (Eimeria tenella). Coccidiosis is known to have a negative impact on the economy. Coccidiosis is controlled using anticoccidial drugs, antibiotics, and vaccines.
Arwa Elnaggar, Hala Mahmoud, Sahar Saber
doaj +1 more source
Different Types of Vaccines against Pestiviral Infections: “Barriers” for “Pestis”
The genus Pestivirus of the family Flaviviridae mainly comprises classical swine fever virus (CSFV), bovine viral diarrhea virus 1 (BVDV-1), BVDV-2, border disease virus (BDV), and multiple new pestivirus species such as atypical porcine pestivirus (APPV)
Mengqi Yuan +6 more
doaj +1 more source
Perspectives of Next-Generation Live-Attenuated Rift Valley Fever Vaccines for Animal and Human Use
Live-attenuated Rift Valley fever (RVF) vaccines transiently replicate in the vaccinated host, thereby effectively initiating an innate and adaptive immune response.
Paul J. Wichgers Schreur +4 more
doaj +1 more source

