Results 241 to 250 of about 43,630 (288)

Flagellins as Vaccine Adjuvants and Cancer Immunotherapy: Recent Advances and Future Prospects

open access: yesImmunology, EarlyView.
The figure depicts the role of flagellin in immune cells. Flagellin interacts with TLR5, resulting in the formation of homodimers and the recruitment of MyD88, which activates the IκB and MAPK signalling pathways. This results in the activation of NF‐κB and AP‐1, producing TNF‐α, IL‐6, IL‐8, and IL‐12.
Asma Talukder   +4 more
wiley   +1 more source

Acute Plasmodium yoelii 17XNL Infection During BCG Vaccination Limits T Cell Responses and Mycobacterial Growth Inhibition

open access: yesImmunology, EarlyView.
Tuberculosis and malaria overlap in many sub‐Saharan African countries where BCG vaccination is routinely administered. The aim of this study was to determine whether the timing of BCG vaccination in relation to a malaria infection has implications for BCG vaccine efficacy.
Emily Tangie   +7 more
wiley   +1 more source

Field Trial of Combined Measles and Rubella Live Attenuated Vaccine

open access: bronze, 2002
Yoshinao Takeuchi   +5 more
openalex   +2 more sources

Should We Advance Our Understanding of Immunoglobulin E in Viral Immunity?

open access: yesImmunology, EarlyView.
Immunoglobulin E has been extensively studied in allergies and parasitic diseases. Antigen‐specific IgE has been identified as part of the humoral response to viruses. This revision speculates on possible functionalities for IgE, such as neutralisation, cytotoxicity and immunopathology of viral diseases, and provide insights about gaps to fill in ...
Amanda Izeli Portilho   +3 more
wiley   +1 more source

VACCINATION OF HUMAN VOLUNTEERS WITH MONOVALENT AND TETRAVALENT LIVE-ATTENUATED DENGUE VACCINE CANDIDATES

open access: bronze, 2003
Wellington Sun   +10 more
openalex   +1 more source

Validating an Index of Selection Bias for Proportions in Non‐Probability Samples

open access: yesInternational Statistical Review, EarlyView.
Summary Fast online surveys without sampling frames are becoming increasingly important in survey research. Their recruitment methods result in non‐probability samples. As the mechanism of data generation is always unknown in such samples, the problem of non‐ignorability arises making vgeneralisation of calculated statistics to the population of ...
Angelina Hammon, Sabine Zinn
wiley   +1 more source

Scaling up home‐visiting to promote early childhood development and prevent violence in Rwanda: a hybrid type‐2 effectiveness‐implementation trial

open access: yesJournal of Child Psychology and Psychiatry, EarlyView.
Background Children in impoverished families–especially those affected by violence–face risks to healthy development. In the years of strong economic recovery since the 1994 Genocide Against the Tutsi, the Rwandan Government has invested in early child development, social and child protection and violence prevention, but few strategies for scaling ...
Candace J. Black   +14 more
wiley   +1 more source

Systemic treatment of immune checkpoint inhibitor‐induced psoriasis: Inference‐based guidance

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
When managing psoriasis, induced or exacerbated by ICI therapy for cancer, there are concerns regarding immunosuppression from systemic agents for the treatment of psoriasis and the potential impact on ICI efficacy. No direct, high‐level evidence exists to address these concerns.
Kim A. Papp   +14 more
wiley   +1 more source

The Roles and Clinical Significance of Major Hepatic‐Derived Metabolites in Hepatocellular Carcinoma

open access: yesJournal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Hepatocellular carcinoma (HCC) is increasingly recognized as a metabolically orchestrated malignancy, in which hepatic‐derived metabolites function not only as byproducts of liver physiology but also as active modulators of tumor biology.
Rui Sun   +5 more
wiley   +1 more source

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