Results 221 to 230 of about 99,732 (351)

Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

Medicinal Research Reviews, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur, Mandeep Rana, Sakshi Vanjani, Kei‐Chi Liou, Rajeev Taliyan, Kunal Nepali, Chih‐Hao Yang   +6 more
wiley   +1 more source

Prospective study of live attenuated vaccines for patients receiving immunosuppressive agents. [PDF]

PLoS One, 2020
Kamei K, Miyairi I, Ishikura K, Ogura M, Shoji K, Arai K, Ito R, Kawai T, Ito S.   +8 more
europepmc   +1 more source

Chimeric Hemagglutinin-Based Live-Attenuated Vaccines Confer Durable Protective Immunity against Influenza A Viruses in a Preclinical Ferret Model. [PDF]

Vaccines (Basel), 2021
Liu WC, Nachbagauer R, Stadlbauer D, Strohmeier S, Solórzano A, Berlanda-Scorza F, Innis BL, García-Sastre A, Palese P, Krammer F, Albrecht RA.   +10 more
europepmc   +1 more source

Social and cultural considerations for the restoration of ‘lost’ tree species: The fall and rise of elm

People and Nature, EarlyView.
Abstract Attempts to address biodiversity loss have led to ecosystem and species restoration efforts. Tree species restoration is particularly relevant because of increasing threats from pests and pathogens. However, there are different notions of ‘loss’, as well as sociocultural considerations, including social acceptability, which are often neglected
Fritha West, Rehema M. White, Althea L. Davies, Richard Buggs, Mariella Marzano   +4 more
wiley   +1 more source

The Strategies Used by Animal Viruses to Antagonize Host Antiviral Innate Immunity: New Clues for Developing Live Attenuated Vaccines (LAVs). [PDF]

Vaccines (Basel)
Chen N, Zhang B.
europepmc   +1 more source

Reverse genetics approaches for the development of mammarenavirus live-attenuated vaccines. [PDF]

Curr Opin Virol, 2020
Ye C, de la Torre JC, Martinez-Sobrido L.   +2 more
europepmc   +1 more source

From HBV to MASLD Cirrhosis: Mechanistic Insights and Therapeutic Strategies

Portal Hypertension &Cirrhosis, EarlyView.
This review examines the epidemiological shift from hepatitis B virus (HBV) to metabolic dysfunction‐associated steatotic liver disease (MASLD) as the leading cause of cirrhosis globally. It highlights the distinct pathogenic mechanisms between HBV and MASLD cirrhosis and discusses evolving diagnostic tools and therapeutic strategies tailored to the ...
Hanqi Yu, Hongfan Ding, Yang Huang, Haoze Cao, Yuan Ding, Weilin Wang   +5 more
wiley   +1 more source

Establishment of an In-House Indirect Enzyme-Linked Immunosorbent Assay to Detect Antibodies Against African Horse Sickness Based on Monovalent and Polyvalent Live Attenuated Vaccines During the First Outbreak in Thailand. [PDF]

Animals (Basel)
Punyadarsaniya D, Taesuji M, Rattanamas K, Ruenphet S.   +3 more
europepmc   +1 more source

Immunogenicity of Live Attenuated B. pertussis BPZE1 Producing the Universal Influenza Vaccine Candidate M2e

, 2013
Hana Kammoun, X. Roux, Dominique Raze, Anne‐Sophie Debrie, Marina De Filette, Tine Ysenbaert, Nathalie Mielcarek, Xavier Saelens, Walter Fiers, Camille Locht   +9 more
openalex   +2 more sources

A Canarypox Vector Expressing Cytomegalovirus (CMV) Glycoprotein B Primes for Antibody Responses to a Live Attenuated CMV Vaccine (Towne) [PDF]

, 1999
Stuart P. Adler, Stanley A. Plotkin, Éva Gönczöl, M. Cadoz, Claude Méric, Jian Ben Wang, P. Dellamonica, Al M. Best, John M. Zahradnik, S Pincus, Klára Berencsi, William I. Cox, Zsófia Gyulai   +12 more
openalex   +1 more source