Results 261 to 270 of about 91,730 (350)

Beyond PD‐1: Mechanisms of Resistance to Checkpoint Blockade in Classical Hodgkin Lymphoma and Next‐Generation Immune Strategies

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT PD‐1 inhibitors have reshaped the treatment landscape of classical Hodgkin lymphoma, yet a substantial proportion of patients exhibit primary or acquired resistance driven by tumor‐intrinsic alterations, immunosuppressive microenvironmental signals, metabolic constraints, and EBV‐mediated modulation.
Santino Caserta   +12 more
wiley   +1 more source

Reining in strangles: Absence of disease in horses vaccinated with a DIVA‐compatible recombinant fusion protein vaccine, Strangvac, following natural exposure to Streptococcus equi subspecies equi

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Strangles, caused by Streptococcus equi subspecies equi (S. equi), is a prevalent infectious disease of horses. This is the first report on the use of a new vaccine, Strangvac, in a natural outbreak of strangles. Objectives To measure the effects of Strangvac vaccination during an outbreak of strangles at a Swedish farm.
Gittan Gröndahl   +11 more
wiley   +1 more source

Perspectives on Pertussis Prevention

open access: yes
Acta Paediatrica, EarlyView.
Ulrich Heininger
wiley   +1 more source

Protein nanoparticles assemble in plants, display antigenic viral peptides, and produce an epitope‐specific immune response

open access: yesThe FEBS Journal, EarlyView.
Current methods to control porcine reproductive and respiratory syndrome, a disease affecting pigs, are insufficient and a safer, more effective vaccine is needed. This study describes the design and plant production of a self‐assembling protein nanoparticle vaccine candidate against this disease.
Jordan T. VanderBurgt   +5 more
wiley   +1 more source

‘I Don't Want Another Five Years of “The Only Thing We Talk About Is Brexit”’: The Dynamics of EU (De)politicisation in Post‐Brexit Britain

open access: yesJCMS: Journal of Common Market Studies, EarlyView.
Abstract The 2016 Brexit referendum was a watershed moment for the politicisation of the European Union (EU) in the United Kingdom. Much has been written about the politicising effects of the referendum, along with the Leave result's subsequent contestation in the media as well as in national and European election cycles.
Anne‐Marie Houde, Louis Stockwell
wiley   +1 more source

The association between COVID‐19 and incident gestational diabetes (GDM): A population‐based case–control study of the National Health Insurance Research Database in Taiwan

open access: yesJournal of Diabetes Investigation, EarlyView.
Our study found no evidence that COVID‐19 infection is linked to gestational diabetes; however, it shows some evidence of an association between vaccination and a reduced risk. ABSTRACT Background Reports suggested that diabetes could be a complication arising from COVID‐19; however, the relationship between COVID‐19 and the development of gestational ...
Liang‐Yu Lin   +4 more
wiley   +1 more source

The “Reducing Inflammation for Greater Health Trial (RIGHT)” Study—Concept, Rationale, and Design

open access: yesJournal of the American Geriatrics Society, EarlyView.
ABSTRACT The Reducing Inflammation for Greater Health Trial's (RIGHT) study is a single‐center, randomized, double‐blind, placebo‐controlled trial designed to test whether clazkizumab, an interleukin‐6 (IL‐6) inhibitor, can improve or slow decline in physical, cognitive, and vascular function in older adults, when compared to a placebo.
Sebastian E. Sattui   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy