Results 101 to 110 of about 1,304,888 (335)

Phenotyping Healthcare Use 2–3 Decades Before the First Multiple Sclerosis Demyelinating Event

Annals of Clinical and Translational Neurology, Volume 12, Issue 8, Page 1585-1594, August 2025.
ABSTRACT Objective Phenotype hospital, physician, and emergency department (ED) visits by diagnoses and specialty up to 29 years pre‐multiple sclerosis (MS) onset versus a matched population without MS. Methods We identified people with MS (PwMS) using population‐based administrative data from Ontario, Canada (1991–2020).
Helen Tremlett, Karl Everett, Colleen J. Maxwell, Feng Zhu, Ayesha Asaf, Ping Li, Kyla A. McKay, Yinshan Zhao, Ruth Ann Marrie   +8 more
wiley   +1 more source

Environmental Human Rights in New York’s Constitution [PDF]

, 2017
There is an environmental case to be made in favor of convening a Constitutional Convention. On the 200th anniversary birth of Henry David Thoreau, we can remember his admonition: “Live in each season as it passes; breathe the air, drink the drink, taste
Robinson, Nicholas A.
core   +1 more source

Factors for Rituximab Refractoriness in AQP4‐IgG+ NMOSD: A Cohort Study

Annals of Clinical and Translational Neurology, Volume 12, Issue 8, Page 1566-1574, August 2025.
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a severe autoimmune condition of the central nervous system (CNS), often associated with aquaporin‐4 antibodies (AQP4‐IgG). Rituximab, a CD20+ B‐cell depleting monoclonal antibody, is widely used as first‐line therapy.
Mariano Marrodan, María A. Piedrabuena, María A. Zarate, Sofía Rodríguez Murúa, Ezequiel I. Surace, Mauricio F. Farez, Marcela P. Fiol, María C. Ysrraelit, Jorge Correale   +8 more
wiley   +1 more source

Safety of efavirenz in the first trimester of pregnancy: an updated systematic review and meta-analysis [PDF]

, 2011
Article approval pendingEvidence of the risk of birth defects with efavirenz use is limited. We updated a meta-analysis of birth defects in infants with first trimester efavirenz exposure up to July 2011.
Alexandra Calmy, Areechokchai, Bera, Blood, Bussmann, Ekouevi, Floridia, Ford, Jeantils, Lynne Mofenson, Machado, Nathan Ford, Patel, Rossouw, Townsend   +14 more
core   +2 more sources

BCS1L‐Associated Disease: 5′‐UTR Variant Shifts the Phenotype Towards Axonal Neuropathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To investigate the consequences of a pathogenic missense variant (c.838C>T; p.L280F) and a 5′‐UTR regulatory variant (c.‐122G>T) in BCS1L on disease pathogenesis and to understand how regulatory variants influence disease severity and clinical presentation.
Rotem Orbach, Nunziata Maio, Russell J. Butterfield, A. Reghan Foley, Sarah Silverstein, Yan Li, Katherine Chao, Tanya J. Lehky, Abigail Potticary, Tracey A. Rouault, Sandra Donkervoort, Carsten G. Bönnemann   +11 more
wiley   +1 more source

Continuous Monitoring of Bladder Dysfunction in People With Multiple Sclerosis: Wearables for the Bladder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Bladder dysfunction affects over 85% of people with multiple sclerosis (PwMS), yet current assessment methods are limited to periodic in‐clinic evaluations or subjective patient reports, failing to capture real‐world symptom fluctuations.
Valerie J. Block, Shane Poole, Leah McIntyre, Nikki Sisodia, Chelyn Park, Gabby Joseph, Michelle E. Van Kuiken, Anne M. Suskind, Riley Bove   +8 more
wiley   +1 more source

Improving quality of care and outcome at very preterm birth: the Preterm Birth research programme, including the Cord pilot RCT [PDF]

, 2019
BACKGROUND:Being born very premature (i.e. before 32 weeks’ gestation) has an impact on survival and quality of life. Improving care at birth may improve outcomes and parents’ experiences.
Aarnoudse-Moens, Abraham, Aladangady, Anderson, Armstrong-Buisseret, Arnold, Batey, Bayley, Becker, Beveridge, Bhatt, Bhutta, Bick, Blank, Boere, Bonetti, Bradshaw, Bradshaw, Bradshaw, Brodbeck, Buckley, Cacioppo, Caldwell, Centre for Reviews and Dissemination (CRD), Chalmers, Chalmers, Chalmers, Chalmers, Chhoa, Cialdini, Cochrane Library, Collins, Committee on Obstetric Practice, Coverdale, Cowan, Critchell, Crowe, Dawes, de Melo-Martín, Department of Health and Social Care, Dorling, Droste, Duley, Duley, Duley, Eclampsia Trial Collaborative Group, Eleftheriadou, Faden, Fangerau, Farrar, Farrar, Farrell, Goldenberg, Grein, Gunther, Halliday, Hammersley, Hofmeyr, Hooper, Hooper, Hosono, Hutchon, Hutchon, James Lind Alliance, Jonsdottir, Keller, Lloyd, Lophatananon, Maclean, Manson, Mason, Mason, McCall, Megone, Mercer, Michels, Moe-Byrne, Moser, Murphy, National Institute for Health and Care Excellence (NICE), Neilson, Nishimura, Oddie, O’Donnell, O’Donnell, Papile, Partridge, Perlman, Petrou, Petty, Pfister, Pfister, Polglase, Popovich, Pushpa-Rajah, Pushpa-Rajah, Rabe, Rabe, Rabe, Redshaw, Reynolds, Richmond, Rojas-Reyes, Russell, Saigal, Saigal, Sajadi, Sandin-Bojö, Sawyer, Sawyer, Sawyer, Sawyer, Sawyer, Schenker, Schmidt, Schmidt, Schmölzer, Schoonakker, Shaw, Shea, Siegel, Simkin, Singh, Sloan, Snowdon, Soll, Soll, Soll, Sprigg, Squires, Stevens, Strech, Tan, Tarnow-Mordi, Tarnow-Mordi, Tarnow-Mordi, Te Pas, The James Lind Alliance, Thomas, Thomas, Tong, Treweek, Tuckman, Tuckman, Tyndale-Biscoe, van Teijlingen, Vijayaselvi, Weeks, Wilman, Woolfall, Wyllie, Wyllie, Yoxall, Zeitlin, Zigmond, Ziino   +155 more
core   +3 more sources

Prevalence of orofacial clefts in Korean live births

Obstetrics & Gynecology Science, 2015
The aim of this study was to investigate the prevalence of orofacial clefts and identify the characteristics of other birth defects associated with orofacial clefts in Korea.This study used data from the Congenital Anomaly Survey conducted by the Korea Institute for Health and Social Affairs.
Chung Won Lee, Sun Mi Hwang, You Sun Lee, Mi-Na Kim, Kyung Seo   +4 more
openaire   +3 more sources

Molecular Screening of SCN1A‐Related Seizures in Children With Febrile Seizures: Diagnostic Yield and Variant Distribution

Annals of Clinical and Translational Neurology, Volume 12, Issue 8, Page 1638-1647, August 2025.
ABSTRACT Objective SCN1A‐related seizures first present as febrile seizures (FS). Definitive features emerge later, making early diagnosis challenging. We evaluated the diagnostic yield and clinical characteristics of pathogenic SCN1A variants in FS, and analyzed the effect of variant characteristics on clinical phenotypes required for early ...
Jia Wang, Yang‐Yang Wang, Lin‐Yan Hu, Xiu‐Yu Shi, Wen He, Dan Sun, Baoguang Li, Xiaoming Liu, Sanqing Xu, Lijun Du, Chunhui Tang, Li‐Ping Zou   +11 more
wiley   +1 more source

Changing trends in surgery for ventricular septal defect in Malta [PDF]

, 1997
Congenital heart defects (CHD) comprise the commonest group of malformations and ventricular septal defect (VSD) is the most prevalent type of CHD most frequently requiring corrective surgery.
Grech, Victor E.
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