Results 41 to 50 of about 735,477 (263)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

GÖKÇEADA’DA GÖÇLERİN NÜFUS GELİŞİMİ ve DEĞİŞİMİ ÜZERİNE ETKİLERİ

open access: yesCoğrafi Bilimler Dergisi, 2005
Gökçeada (Imbros) is the biggest island of Turkey in the northeast Aegean Sea. Throughout history, Gökçeada has been the island of immigrant. Gökçeada is the epitome of migration.
Selver ÖZÖZEN KAHRAMAN
doaj   +1 more source

Intermediate node selection for Scatter-Gather VM migration in cloud data center

open access: yesEngineering Science and Technology, an International Journal, 2020
Virtual machine migration is used in cloud computing for server consolidation, system maintenance, opportunistic power savings, and load balancing. Scatter-Gather VM live migration is a new type of virtual machine migration.
Chakravarthy Sudarshan Annadanam   +2 more
doaj   +1 more source

Social Networking in Forced Migration: The Case of Şanlıurfa City

open access: yesSosyal Siyaset Konferansları Dergisi, 2021
Turkey has been undergoing a mass migration since 2011 due to internal turmoil and violence in Syria. Millions of people have been forced to enter Turkey, having been displaced.
Hakan Gülerce, Ekrem Demir
doaj   +1 more source

Traffic-Sensitive Live Migration of Virtual Machines [PDF]

open access: yes2015 15th IEEE/ACM International Symposium on Cluster, Cloud and Grid Computing, 2015
In this paper we address the problem of network contention between the migration traffic and the Virtual Machine (VM) application traffic for the live migration of co-located Virtual Machines. When VMs are migrated with pre-copy, they run at the source host during the migration.
Umesh Deshpande, Kate Keahey
openaire   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

TSMC: A Novel Approach for Live Virtual Machine Migration

open access: yesJournal of Applied Mathematics, 2014
Cloud computing attracted more and more attention in recent years, and virtualization technology is the key point for deploying infrastructure services in cloud environment.
Jiaxing Song   +3 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

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