Results 61 to 70 of about 735,477 (263)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Provisioning of Live Container Migration in Edge/Cloud Environments: Techniques and Challenges

Journal of Applied Engineering and Technological Science
Containers have become increasingly popular in the virtualization landscape. Their lightweight nature and fast deployment behavior make them an efficient alternative to traditional hypervisor-based virtual machines.
Radhwan Al-Bayram, Rawaa Qasha
doaj   +1 more source

A Location Selection Policy of Live Virtual Machine Migration for Power Saving and Load Balancing

The Scientific World Journal, 2013
Green cloud data center has become a research hotspot of virtualized cloud computing architecture. And load balancing has also been one of the most important goals in cloud data centers. Since live virtual machine (VM) migration technology is widely used
Jia Zhao, Yan Ding, Gaochao Xu, Liang Hu, Yushuang Dong, Xiaodong Fu   +5 more
doaj   +1 more source

Observation of Dynamic Cellular Migration of the Medial Edge Epithelium of the Palatal Shelf in vitro

Frontiers in Physiology, 2019
Palatal fusion is a critical step during palatogenesis. In this fusing interface, the epithelial sheets need to be removed in order to achieve mesenchymal continuity.
Gozo Aoyama, Hiroshi Kurosaka, Ayaka Oka, Kohei Nakatsugawa, Sayuri Yamamoto, Safiye Esra Sarper, Safiye Esra Sarper, Yu Usami, Satoru Toyosawa, Toshihiro Inubushi, Yukako Isogai, Takashi Yamashiro   +11 more
doaj   +1 more source

Chemotaxis migration and morphogenesis of living colonies [PDF]

The European Physical Journal E, 2013
Development of forms in living organisms is complex and fascinating. Morphogenetic theories that investigate these shapes range from discrete to continuous models, from the variational elasticity to time-dependent fluid approach. Here a mixture model is chosen to describe the mass transport in a morphogenetic gradient: it gives a mathematical ...
openaire   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Seamless transitions: a comprehensive review of live migration technologies

Journal of Cloud Computing: Advances, Systems and Applications
Live migration, a technology enabling seamless transition of operational computational entities between various hosts while preserving continuous functionality and client connectivity, has been the subject of extensive research. However, existing reviews
Sima Attar-Khorasani, Lincoln Sherpa, Matthias Lieber, Siavash Ghiasvand   +3 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source